Thieno[2,3-c]pyrrol-4-one derivatives as erk inhibitors

The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the treatment of cancer.

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Main Authors Zhao, Gaiying, Joseph, Sajan, Mcmillen, William T, Rodriguez, Michael John, Mclean, Johnathan Alexander, Cortez, Guillermo S
Format Patent
LanguageEnglish
Published 21.12.2018
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Abstract The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the treatment of cancer.
AbstractList The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in the treatment of cancer.
Author Cortez, Guillermo S
Joseph, Sajan
Rodriguez, Michael John
Mclean, Johnathan Alexander
Zhao, Gaiying
Mcmillen, William T
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– fullname: Cortez, Guillermo S
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Snippet The present invention provides thieno[2,3-c]pyrrol-4-one compounds that inhibit activity of extracellular-signal-regulated kinase (ERK) and may be useful in...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Thieno[2,3-c]pyrrol-4-one derivatives as erk inhibitors
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