STABILIZED LIPID FORMULATION OF APOPTOSIS PROMOTER

• Main Authors: SANZGIRI, YESHWANT, FICKES, MICHAEL, HEEMSTRA, KATHERINE, FISCHER, CRISTINA, HAIGHT, ANTHONY R, SCHMITT, ERIC, ZHANG, GEOFF, TONG, PING, ZHOU, DELIANG, CATRON, NATHANIEL
• Format: Patent
• Language: English
• Published: 29.11.2013
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

596047 Disclosed herein is an orally deliverable pharmaceutical composition comprising a Bcl-2 family protein inhibitory compound, e.g., ABT-263, a heavier-chalcogen antioxidant and a substantially non-aqueous lipid carrier, wherein said compound and said antioxidant are in solution in the carrier....