Peptide vectors for delivering paclitaxel

• Main Authors: SHEN, YEELANA, COMSTOCK, JEANNE MARY, KIM, SUN H, DONG, ZHENG XIN
• Format: Patent
• Language: English
• Published: 28.01.2011
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

A compound according to the formula "X-B1-B2-B3-B4-Z" wherein: X is paclitaxel or a paclitaxel derivative, B1, B2, B3, and B4 are independently for each occurrence: (Doc)m, (Aepa)n, -(C(O)-A1-A2-A3-A4-A5-C(O))s-, or (amino acid)p; wherein the amino acid is selected from the group consistin...