Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith

Disclosed is a compound having the formula (I) wherein the substituents are described in the specification. Also disclosed is the use of the compound in a preparation for treating or preventing a metabolic disease, cancer, a cardiovascular disease, a renal disease, an autoimmune disease, macular deg...

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Main Authors AYALA, LETICIA, HEDGE, SAYEE, KOIS, ADAM, CLAREEN, STEVEN S, NADOLNY, LISA, HUGHES, KEVIN, PLANTEVIN-KRENITSKY, VERONIQUE, MCCARRICK, MEG, SATOH, YOSHITAKA, SAHASRABUDHE, KIRAN, ALBERS, RONALD, SAPIENZA, JOHN, SLOSS, MARIANNE, SUDBECK, ELISE, HENDERSON, IAN, HILGRAF, ROBERT, DELGADO MEDEROS, MARIA M, COLE, ANDREW G, PALANKI, MOORTHY, WRIGHT, JONATHAN
Format Patent
LanguageEnglish
Published 29.01.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract Disclosed is a compound having the formula (I) wherein the substituents are described in the specification. Also disclosed is the use of the compound in a preparation for treating or preventing a metabolic disease, cancer, a cardiovascular disease, a renal disease, an autoimmune disease, macular degeneration, ischemia-reperfusion injury, pain or a pain-related syndrome, disease-related wasting, an asbestos-related condition, central nervous system injury/damage or pulmonary hypertension.
AbstractList Disclosed is a compound having the formula (I) wherein the substituents are described in the specification. Also disclosed is the use of the compound in a preparation for treating or preventing a metabolic disease, cancer, a cardiovascular disease, a renal disease, an autoimmune disease, macular degeneration, ischemia-reperfusion injury, pain or a pain-related syndrome, disease-related wasting, an asbestos-related condition, central nervous system injury/damage or pulmonary hypertension.
Author DELGADO MEDEROS, MARIA M
WRIGHT, JONATHAN
COLE, ANDREW G
KOIS, ADAM
ALBERS, RONALD
SUDBECK, ELISE
HILGRAF, ROBERT
MCCARRICK, MEG
CLAREEN, STEVEN S
SLOSS, MARIANNE
SAPIENZA, JOHN
SATOH, YOSHITAKA
SAHASRABUDHE, KIRAN
HEDGE, SAYEE
PALANKI, MOORTHY
NADOLNY, LISA
HENDERSON, IAN
HUGHES, KEVIN
PLANTEVIN-KRENITSKY, VERONIQUE
AYALA, LETICIA
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– fullname: PALANKI, MOORTHY
– fullname: WRIGHT, JONATHAN
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Snippet Disclosed is a compound having the formula (I) wherein the substituents are described in the specification. Also disclosed is the use of the compound in a...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
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