Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith

Disclosed is a compound having the formula (I) wherein the substituents are described in the specification. Also disclosed is the use of the compound in a preparation for treating or preventing a metabolic disease, cancer, a cardiovascular disease, a renal disease, an autoimmune disease, macular deg...

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Main Authors AYALA, LETICIA, HEDGE, SAYEE, KOIS, ADAM, CLAREEN, STEVEN S, NADOLNY, LISA, HUGHES, KEVIN, PLANTEVIN-KRENITSKY, VERONIQUE, MCCARRICK, MEG, SATOH, YOSHITAKA, SAHASRABUDHE, KIRAN, ALBERS, RONALD, SAPIENZA, JOHN, SLOSS, MARIANNE, SUDBECK, ELISE, HENDERSON, IAN, HILGRAF, ROBERT, DELGADO MEDEROS, MARIA M, COLE, ANDREW G, PALANKI, MOORTHY, WRIGHT, JONATHAN
Format Patent
LanguageEnglish
Published 29.01.2010
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Disclosed is a compound having the formula (I) wherein the substituents are described in the specification. Also disclosed is the use of the compound in a preparation for treating or preventing a metabolic disease, cancer, a cardiovascular disease, a renal disease, an autoimmune disease, macular degeneration, ischemia-reperfusion injury, pain or a pain-related syndrome, disease-related wasting, an asbestos-related condition, central nervous system injury/damage or pulmonary hypertension.
Bibliography:Application Number: NZ20060556654