Hybrid polypeptides with selectable properties

Provided is a hybrid polypeptide exhibiting at least two hormonal activities, said hybrid polypeptide comprising a first bio-active peptide hormone module covalently linked to at least one additional bio-active peptide hormone module; wherein: the bio-active peptide hormone modules are independently...

Full description

Saved in:
Bibliographic Details
Main Authors LEWIS, DIANA Y, SOARES, CHRISTOPHER J, MACK, CHRISTINE M, DAESOUZA, LAWRENCE J, LEVY, ODILE ESTHER, HANLEY, MICHAEL R, GHOSH, SOUMITRA S, JODKA, CAROLYN M, PARKES, DAVID G
Format Patent
LanguageEnglish
Published 30.10.2009
Subjects
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
SUGARS
Online AccessGet full text

Cover

More Information
Summary:Provided is a hybrid polypeptide exhibiting at least two hormonal activities, said hybrid polypeptide comprising a first bio-active peptide hormone module covalently linked to at least one additional bio-active peptide hormone module; wherein: the bio-active peptide hormone modules are independently selected from the group consisting of: component peptide hormones, fragments of component peptide hormones that exhibit at least one hormonal activity of the component peptide hormones, analogs and derivatives of component peptide hormones that exhibit at least one hormonal activity of the component peptide hormones, and fragments of analogs and derivatives of component peptide hormones that exhibit at least one hormonal activity of theÀ component peptide hormones; the component peptide hormones are independently selected from at least two of the group consisting of: amylin and exendin-4; and both of the bio-active peptide hormone modules exhibits at least one hormonal activity of a component peptide hormone.
Bibliography:Application Number: NZ20050548978