PREPARATION OF BICYCLIC AMINO CARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES THEREFOR

• Main Authors: URBACH, HANSJORG, HENNING, RAINER
• Format: Patent
• Language: English
• Published: 21.12.1990
• Edition: 4
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

Compounds of the formula I in which n is 1, 2 or 3, R denotes acyl and R denotes alkyl, cycloalkyl, aralkyl or another carboxyl protecting group are prepared by free-radical cyclisation of compounds of the formula II in which n, R and R are as defined above and Hal denotes chlorine, bromine or iodin...