NYE PYRANOKINOLINONDERIVATER OG FREMGANGSMAATE TIL DERES FREMSTILLING

PURPOSE: To obtain a medicinal composition useful for inhibiting an obstruction of airway or an excessive secretion of mucus, containing a specific pyranoquinoline derivative. CONSTITUTION: This composition contains 9-ethyl-6,9-dihydro-4,6-dioxo-10propyl-4 H-pyrano(3,2-g)quinoline-2,8-dicarboxylic a...

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Bibliographic Details
Main Authors CAIRNS, HUGH, COX, DAVID
Format Patent
LanguageNorwegian
Published 07.11.1978
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:PURPOSE: To obtain a medicinal composition useful for inhibiting an obstruction of airway or an excessive secretion of mucus, containing a specific pyranoquinoline derivative. CONSTITUTION: This composition contains 9-ethyl-6,9-dihydro-4,6-dioxo-10propyl-4 H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid as an active component. An administration dose is 0.001-50mg per 1kg of body weight or 0.01-1,000mg, especially 1-60mg per 1 day for a person. The compound of formula I is produced by selectively hydrolyzing or oxidizing a compound of formula II (D and D) are each a group capable of being hydrolyzed or oxidized to COOH, or either is the above group and the other is COOH), or cyclizing a compound of formula III or IV.
Bibliography:Application Number: NO19780001549