2,3-dihydro-1,4-benzodioksin-5-yl-piperazinderivater med 5-HT1A-antagonistisk aktivitet og farmasöytisk sammensetning inneholdende dem

• Main Authors: MOS, JOHANNES, SCHIPPER, JACQUES, HARTOG, JAN, STEEN, BARTHOLOMEUS JOHANNES VAN
• Format: Patent
• Language: Norwegian
• Published: 05.01.1998
• Edition: 6
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention is concerned with compounds having 5-HT1A antagonistic activity useful in treating CNS disorders and having formula 2 wherein R1 is halogen, lower alkyl or alkoxy, hydroxy, trifluotomethyl or cyano, m has the value 1 or 2 and n has the value 0 or 1, A represents an alkylene cha...