ANALOGIFREMGANGSMAATE FOR FREMSTILLING AV TERAPEUTISK AKTIVE L-AMINOSYRE-DERIVATER
Compounds of the formula wherein R1 is hydrogen, alkyl of 1 to 6 carbon atoms, or phenyl(alkyl of 1 to 6 carbon atoms); R2 is hydrogen, alkyl of 1 to 4 carbon atoms or phenyl(alkyl of 1 to 6 carbon atoms); R3 is hydrogen or alkyl of 1 to 6 carbon atoms; n and m are each independently 0, 1 or 2, the...
Saved in:
Main Authors | , , , , , |
---|---|
Format | Patent |
Language | Norwegian |
Published |
16.10.1989
|
Edition | 4 |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Compounds of the formula wherein R1 is hydrogen, alkyl of 1 to 6 carbon atoms, or phenyl(alkyl of 1 to 6 carbon atoms); R2 is hydrogen, alkyl of 1 to 4 carbon atoms or phenyl(alkyl of 1 to 6 carbon atoms); R3 is hydrogen or alkyl of 1 to 6 carbon atoms; n and m are each independently 0, 1 or 2, the sum of n and m being 1 or 2; X, Y and Z are each independently oxygen, sulfur, -NR4-, =CR5-, -CHR5-, provided that only one of X, Y and Z is O, S, and one or two of X, Y and Z are -NR4-; R4 is hydrogen or alkyl of 1 to 4 carbon atoms; and R5 is hydrogen or, together with a vicinal radical R5, a phenyl ring, or when m and n are both 1, the dihydro form with its double bond in conjugation with the C-term=inal carboxylic group; or a non-toxic, pharmacologically acceptable salt thereof. The compounds as well as their salts are useful as antihypertensives. |
---|---|
AbstractList | Compounds of the formula wherein R1 is hydrogen, alkyl of 1 to 6 carbon atoms, or phenyl(alkyl of 1 to 6 carbon atoms); R2 is hydrogen, alkyl of 1 to 4 carbon atoms or phenyl(alkyl of 1 to 6 carbon atoms); R3 is hydrogen or alkyl of 1 to 6 carbon atoms; n and m are each independently 0, 1 or 2, the sum of n and m being 1 or 2; X, Y and Z are each independently oxygen, sulfur, -NR4-, =CR5-, -CHR5-, provided that only one of X, Y and Z is O, S, and one or two of X, Y and Z are -NR4-; R4 is hydrogen or alkyl of 1 to 4 carbon atoms; and R5 is hydrogen or, together with a vicinal radical R5, a phenyl ring, or when m and n are both 1, the dihydro form with its double bond in conjugation with the C-term=inal carboxylic group; or a non-toxic, pharmacologically acceptable salt thereof. The compounds as well as their salts are useful as antihypertensives. |
Author | WIEDEMANN, INGRID ROOS, OTTO GAIDA, WOLFRAM LOESEL, WALTER HOEFKE, WOLFGANG SCHNORRENBERG, GERD |
Author_xml | – fullname: LOESEL, WALTER – fullname: HOEFKE, WOLFGANG – fullname: SCHNORRENBERG, GERD – fullname: GAIDA, WOLFRAM – fullname: WIEDEMANN, INGRID – fullname: ROOS, OTTO |
BookMark | eNqFi8sKwjAQAHPQg69vMD-QQxUKHre6iUvTRDax4KkUiSdJC_X_UcG7p4FhZilmechpIRgcWG9IMzYGnAkNQESpPcuvCpGsJWcktDIiwwWvkUItoY7UorQKGnI-3BjVCZnaz8trMX_0zyltflyJrcZ4PKs0Dl2axv6ecnp1zhflriwOVbX_X7wBiUsxRg |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
Edition | 4 |
ExternalDocumentID | NO162619BB |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_NO162619BB3 |
IEDL.DBID | EVB |
IngestDate | Fri Jul 19 14:58:54 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | Norwegian |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_NO162619BB3 |
Notes | Application Number: NO19840000212 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19891016&DB=EPODOC&CC=NO&NR=162619B |
ParticipantIDs | epo_espacenet_NO162619BB |
PublicationCentury | 1900 |
PublicationDate | 19891016 |
PublicationDateYYYYMMDD | 1989-10-16 |
PublicationDate_xml | – month: 10 year: 1989 text: 19891016 day: 16 |
PublicationDecade | 1980 |
PublicationYear | 1989 |
RelatedCompanies | BOEHRINGER INGELHEIM KG |
RelatedCompanies_xml | – name: BOEHRINGER INGELHEIM KG |
Score | 2.3999722 |
Snippet | Compounds of the formula wherein R1 is hydrogen, alkyl of 1 to 6 carbon atoms, or phenyl(alkyl of 1 to 6 carbon atoms); R2 is hydrogen, alkyl of 1 to 4 carbon... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
Title | ANALOGIFREMGANGSMAATE FOR FREMSTILLING AV TERAPEUTISK AKTIVE L-AMINOSYRE-DERIVATER |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19891016&DB=EPODOC&locale=&CC=NO&NR=162619B |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV1LT8MwDLbGQMANBmi8c0C9VTCWdeuhQmmbbgOaTm1XjdPU1xCXbmJF_H2cqgMuu0WJYiWWHPtz_AC4Q9CR9KTTvZ8NEpWmi74a652uSnMEB9LR_1j1jHSFNprS51lv1oD3TS5MVSf0uyqOiBKVoryX1Xu9-nNi2VVs5fo--cCp5ZMTGraSxXX4jwSjim0afOLZnqVYliE8RfhGR5NQwdyBXWlDyyL7PDJlSsrqvz5xjmBvgqSK8hgaxbIFB9am7VoL9t36txuHteCtT8Bngsm2BY7P3SETw8BlLOQEIRyRU0EoQbkYEhYRtE_ZhE_DcfBC0IIbR5y8qswdCy9487lqI3KLcK9_CrcOD62Rioeb_7JhLrz6Emb3DJrFssjbQBZ6nKFJo8V6ktOUZgkd6PFgEaf9x4eUJvE5tLdRudi-dAmHVSyVjNzQrqBZfn7l16h8y-SmYtwP8aqDeQ |
link.rule.ids | 230,309,786,891,25594,76903 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdZ3NT8IwFMBfEI14U9TgJzuY3RYFxsYOi-m-AGEd2caCJ7IviJdBZMZ_39dmqBduTZs27Ute-36vr30ATwgdSZ853dVskEhyulKlWOv0JDlHOGCO_i7PGelSZTSX3xb9RQ3W-7cw_J_Qb_45ImpUivpe8v16--fEsnhs5e45-cCqzasT6paYxVX4D4NR0TJ0e-ZZnimapk49kfp6R2GoYBzBsYo8yDkpMtiTlO3_88Q5h5MZDlWUF1ArNk1omPu0a004davbbixWire7BJ9QwtIWOL7tDgkdBi4hoS0gwgmsKggZlNOhQCIB7VMys-fhOJgIaMGNI1uYSsQdUy94923JQnKLsK9_BW3HDs2RhJNb_ophSb1qEUbvGurFpshbIKy0OEOTRom1JJdTOUvkgRYPVnGqdl9SOYlvoHVolNvDTW1ojEJ3usSZT-7gjMdVsSgO5R7q5edX_oAHcZk8ciH-ADu3hmM |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=ANALOGIFREMGANGSMAATE+FOR+FREMSTILLING+AV+TERAPEUTISK+AKTIVE+L-AMINOSYRE-DERIVATER&rft.inventor=LOESEL%2C+WALTER&rft.inventor=HOEFKE%2C+WOLFGANG&rft.inventor=SCHNORRENBERG%2C+GERD&rft.inventor=GAIDA%2C+WOLFRAM&rft.inventor=WIEDEMANN%2C+INGRID&rft.inventor=ROOS%2C+OTTO&rft.date=1989-10-16&rft.externalDBID=B&rft.externalDocID=NO162619BB |