ANALOGIFREMGANGSMAATE VED FREMSTILLING AV TERAPEUTISK AKTIVT 5-(4-PYRIDYL-6-(4-FLUORFENYL)-2,3-DIHYDROIMIDAZO-(2,1-B)-TIAZOL

• Main Authors: LANTOS, IVAN, BENDER, PAUL ELLIOT
• Format: Patent
• Language: Norwegian
• Published: 17.09.1984
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

5(4-Pyridyl)-6(4-fluorophenyl)-2,3-dihydroimidazo -[2,1-b] thiazole has significant antiarthritic and immunoregulatory activity compared with its 5,6-transposed isomer. The compound is prepared by reacting 4-(4-pyridyl-5-[4-fluorophenyl) -2-mercaptoimidazole with a reactive ethylene dihalide then se...