EL USO DE INHIBIDORES DE LA ACTIVIDAD O FUNCIÓN DE LA PI3K

La invención se refiere a nuevos usos de inhibidores de la PI3K, en el que dichos inhibidores tienen una acción inhibidora sobre la isoforma delta de la PI3K para el tratamiento de la inmunopatología en un sujeto que sufre de una enfermedad o trastorno seleccionado entre malaria, leishmaniasis, trip...

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Main Authors ANETTE VON MATT, CHRISTINA HEBACH, NICOLAS SOLDERMANN, ROMAIN WOLF, KLEMENS HÖGENAUER, FRÉDÉRIC ZECRI, NIGEL GRAHAM COOKE, FRÉDÉRIC STAUFFER, ALEXANDER BAXTER SMITH, IAN LEWIS, CHRISTOPH KALIS, NICOLA TIFILLI, PASCAL FURET, ROSS STRANG, FRANK STOWASSER, PAULO ANTONIO FERNANDES GOMES DOS SANTOS
Format Patent
LanguageSpanish
Published 22.12.2014
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Abstract La invención se refiere a nuevos usos de inhibidores de la PI3K, en el que dichos inhibidores tienen una acción inhibidora sobre la isoforma delta de la PI3K para el tratamiento de la inmunopatología en un sujeto que sufre de una enfermedad o trastorno seleccionado entre malaria, leishmaniasis, tripanosomiasis, toxoplasmosis y/o neurocisticercosis, a través de la inhibición funcional de TLR9 del infectado. The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.
AbstractList La invención se refiere a nuevos usos de inhibidores de la PI3K, en el que dichos inhibidores tienen una acción inhibidora sobre la isoforma delta de la PI3K para el tratamiento de la inmunopatología en un sujeto que sufre de una enfermedad o trastorno seleccionado entre malaria, leishmaniasis, tripanosomiasis, toxoplasmosis y/o neurocisticercosis, a través de la inhibición funcional de TLR9 del infectado. The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.
Author ROSS STRANG
NICOLA TIFILLI
ROMAIN WOLF
PAULO ANTONIO FERNANDES GOMES DOS SANTOS
ANETTE VON MATT
KLEMENS HÖGENAUER
FRÉDÉRIC ZECRI
CHRISTOPH KALIS
PASCAL FURET
NIGEL GRAHAM COOKE
CHRISTINA HEBACH
NICOLAS SOLDERMANN
FRANK STOWASSER
ALEXANDER BAXTER SMITH
IAN LEWIS
FRÉDÉRIC STAUFFER
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– fullname: PASCAL FURET
– fullname: ROSS STRANG
– fullname: FRANK STOWASSER
– fullname: PAULO ANTONIO FERNANDES GOMES DOS SANTOS
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Snippet La invención se refiere a nuevos usos de inhibidores de la PI3K, en el que dichos inhibidores tienen una acción inhibidora sobre la isoforma delta de la PI3K...
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MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title EL USO DE INHIBIDORES DE LA ACTIVIDAD O FUNCIÓN DE LA PI3K
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