EL USO DE INHIBIDORES DE LA ACTIVIDAD O FUNCIÓN DE LA PI3K
La invención se refiere a nuevos usos de inhibidores de la PI3K, en el que dichos inhibidores tienen una acción inhibidora sobre la isoforma delta de la PI3K para el tratamiento de la inmunopatología en un sujeto que sufre de una enfermedad o trastorno seleccionado entre malaria, leishmaniasis, trip...
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Format | Patent |
Language | Spanish |
Published |
22.12.2014
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Subjects | |
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Abstract | La invención se refiere a nuevos usos de inhibidores de la PI3K, en el que dichos inhibidores tienen una acción inhibidora sobre la isoforma delta de la PI3K para el tratamiento de la inmunopatología en un sujeto que sufre de una enfermedad o trastorno seleccionado entre malaria, leishmaniasis, tripanosomiasis, toxoplasmosis y/o neurocisticercosis, a través de la inhibición funcional de TLR9 del infectado.
The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject. |
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AbstractList | La invención se refiere a nuevos usos de inhibidores de la PI3K, en el que dichos inhibidores tienen una acción inhibidora sobre la isoforma delta de la PI3K para el tratamiento de la inmunopatología en un sujeto que sufre de una enfermedad o trastorno seleccionado entre malaria, leishmaniasis, tripanosomiasis, toxoplasmosis y/o neurocisticercosis, a través de la inhibición funcional de TLR9 del infectado.
The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject. |
Author | ROSS STRANG NICOLA TIFILLI ROMAIN WOLF PAULO ANTONIO FERNANDES GOMES DOS SANTOS ANETTE VON MATT KLEMENS HÖGENAUER FRÉDÉRIC ZECRI CHRISTOPH KALIS PASCAL FURET NIGEL GRAHAM COOKE CHRISTINA HEBACH NICOLAS SOLDERMANN FRANK STOWASSER ALEXANDER BAXTER SMITH IAN LEWIS FRÉDÉRIC STAUFFER |
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Snippet | La invención se refiere a nuevos usos de inhibidores de la PI3K, en el que dichos inhibidores tienen una acción inhibidora sobre la isoforma delta de la PI3K... |
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Title | EL USO DE INHIBIDORES DE LA ACTIVIDAD O FUNCIÓN DE LA PI3K |
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