N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-D]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-D]PYRIMIDINES AS JANUS KINASE INHIBITORS

THE PRESENT INVENTION RELATES TO N-(HETERO) ARYL-PYRROIIDIFLE DERIVATIVES OF FORMULA I, AS WELL AS THEIR COMPOSITIONS AND METHODS OF USE, WHICH ARE JAK INHIBITORS, SUCH AS SELECTIVE JAK1 INHIBITORS, USEFUL IN THE TREATMENT OF JAK-ASSOCIATED DISEASES INCLUDING, FOR EXAMPLE, INFLAMMATORY AND AUTOIMMUN...

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Main Authors SHEPARD, STACEY, WANG, HAISHENG, SHAO, LIXIN, RODGERS, JAMES D, FOLMER, BEVERLY, ZHU, WENYU, STORACE, LOUIS, ARVANITIS, ARGYRIOS G, GLENN, JOSEPH P
Format Patent
LanguageEnglish
Published 15.03.2016
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract THE PRESENT INVENTION RELATES TO N-(HETERO) ARYL-PYRROIIDIFLE DERIVATIVES OF FORMULA I, AS WELL AS THEIR COMPOSITIONS AND METHODS OF USE, WHICH ARE JAK INHIBITORS, SUCH AS SELECTIVE JAK1 INHIBITORS, USEFUL IN THE TREATMENT OF JAK-ASSOCIATED DISEASES INCLUDING, FOR EXAMPLE, INFLAMMATORY AND AUTOIMMUNE DISORDERS, AS WELL AS CANCER.
AbstractList THE PRESENT INVENTION RELATES TO N-(HETERO) ARYL-PYRROIIDIFLE DERIVATIVES OF FORMULA I, AS WELL AS THEIR COMPOSITIONS AND METHODS OF USE, WHICH ARE JAK INHIBITORS, SUCH AS SELECTIVE JAK1 INHIBITORS, USEFUL IN THE TREATMENT OF JAK-ASSOCIATED DISEASES INCLUDING, FOR EXAMPLE, INFLAMMATORY AND AUTOIMMUNE DISORDERS, AS WELL AS CANCER.
Author SHAO, LIXIN
STORACE, LOUIS
GLENN, JOSEPH P
SHEPARD, STACEY
ARVANITIS, ARGYRIOS G
FOLMER, BEVERLY
ZHU, WENYU
RODGERS, JAMES D
WANG, HAISHENG
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– fullname: RODGERS, JAMES D
– fullname: FOLMER, BEVERLY
– fullname: ZHU, WENYU
– fullname: STORACE, LOUIS
– fullname: ARVANITIS, ARGYRIOS G
– fullname: GLENN, JOSEPH P
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Snippet THE PRESENT INVENTION RELATES TO N-(HETERO) ARYL-PYRROIIDIFLE DERIVATIVES OF FORMULA I, AS WELL AS THEIR COMPOSITIONS AND METHODS OF USE, WHICH ARE JAK...
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SubjectTerms HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-D]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-D]PYRIMIDINES AS JANUS KINASE INHIBITORS
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