PROCESS FOR THE PREPARATION OF 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)-PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE

• Main Authors: KLAUS-HELMUT MOHRS, MIKE MATTHAEUS, JUERGEN STIEHL, MICHAEL LOEGERS, REINHOLD GEHRING, MATHIAS BERWE, JANA LENZ, WERNER HEILMANN, MATTHIAS MUELLER-GLIEMANN, OLIVER KUHN
• Format: Patent
• Language: English
• Published: 31.10.2013
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

THE PRESENT INVENTION RELATES TO A PROCESS FOR PREPARING 4-{ 4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY)-N-METHYLPYRIDINE-2-CARBOXAMIDE AND ITS TOSYLATE SALT. FORMULA (I), WHICH COMPRISES, IN A FIRST STEP, REACTING THE COMPOUND OF THE FORMULA (V) WITH 4-CHLORO-3-TRIFLUOROM...