FIVE- MEMBERED HETEROCYCLES HAVING BIPHENYLSULFONYL SUBSTITUTION, PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC AND MEDICAMENT COMPRISING THEM

• Main Authors: JAN-ROBERT SCHWARK, HANS-WILLI JANSEN, AP SABINE FABER, HANS JOCHEN LANG, ANDREAS WEICHERT, HEINZ-WERNER KLEEMANN
• Format: Patent
• Language: English
• Published: 28.02.2006
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CHEMISTRY; FISHING; FORESTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TRAPPING

COMPOUNDS OF THE FORMULA I FORMULA I IN WHICH THE SYMBOLS HAVE THE MEANINGS INDICATED IN THE CLAIMS, HAVE OUTSTANDING ANTIARRHYTHMIC PROPERTIES AND EXHIBIT A CARDIOPROTECTIVE COMPONENT. THEY CAN PREVENTIVELY INHIBIT OR GREATLY DECREASE THE PATHOPHYSIOLOGICAL PROCESSES IN THE FORMATION OF ISCHEMICALLY INDUCED DAMAGE, IN PARTICULAR IN THE ELICITATION OF ISCHEMICALLY INDUCED CARDIAC ARRHYTHMIAS. MOREOVER, THEY HAVE A POTENT INHIBITORY ACTION ON THE PROLIFERATION OF CELLS.