CRYSTALLINE FORM OF THE P38 KINASE INHIBITOR 2-{4 -[3-(4-CHLORO -2-FLUOROPHENYL) -4-PYRIMIDIN-4 -YL-LH-PYRAZOL -5-YL]PIPERIDIN -1-YL}-2 -OXOETHANOL

• Main Authors: RICHARD R. SCHARTMAN, DOUG H. HOFFMAN
• Format: Patent
• Language: English; Spanish
• Published: 19.12.2006
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

Crystalline form of the p38 kinase inhibitor 2-{4-[3 -(4-chloro -2-fluorophenyl) -4-pyrimidin-4-yl -lH-pyrazol-5 -yl]piperidin -1-yl} -2-oxoethanol can be used, is provided. The crystalline form is a hydrated crystalline form. Also provided are combinations and pharmaceutical compositions comprising...