INTERMEDIATES FOR PREPARING GLYCOGEN PHOSPHORYLASE INHIBITORS

The instant invention provides novel processes and intermediates useful in the preparation of certain N-(indole-2-carbonyl)-beta-alaninamide compounds, which compounds are glycogen phosphorylase inhibitors useful in the treatment of diseases such as hypercholesterolemia, hyperglycemia, hyperinsuline...

Full description

Saved in:
Bibliographic Details
Main Author TOBIASSEN, HARRY ODD
Format Patent
LanguageEnglish
Spanish
Published 06.12.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:The instant invention provides novel processes and intermediates useful in the preparation of certain N-(indole-2-carbonyl)-beta-alaninamide compounds, which compounds are glycogen phosphorylase inhibitors useful in the treatment of diseases such as hypercholesterolemia, hyperglycemia, hyperinsulinemia, hyperlipidemia, hypertension, atherosclerosis, diabetes, diabetic cardiomyopathy, infection, tissue ischemia, myocardial ischemia, and in inhibiting tumor growth. La presente invencion proporciona nuevos procedimientos e intermedios utiles en la preparacion de ciertos compuestos de N-(indol-2-carbonil)-(-alaninamida, siendo dichos compuestos inhibidores de la glucogeno fosforilasa utiles en el tratamiento de enfermedades tales como la hipercolesterolemia, hiperglucemia, hiperinsulinemia, hiperlipidemia, hipertension, aterosclerosis, diabetes, cardiomipatia diabetica, infeccion, isquemia de tejidos, isquemia de miocardio, y en la inhibicion del crecimiento de tumores.
Bibliography:Application Number: MX2004PA06937