INHIBITORS OF INTEGRIN agr;v

Novel biphenyl derivatives of the general formula (I) in which R1, R1', R1'', R2, R2', R3 and n are as defined in claim 1, their stereoisomers and their physiologically acceptable salts or solvates are novel integrin inhibitors which preferentially inhibit the alphavbeta6 integri...

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Bibliographic Details
Main Author ALFRED JONCZYK
Format Patent
LanguageEnglish
Spanish
Published 29.01.2004
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Novel biphenyl derivatives of the general formula (I) in which R1, R1', R1'', R2, R2', R3 and n are as defined in claim 1, their stereoisomers and their physiologically acceptable salts or solvates are novel integrin inhibitors which preferentially inhibit the alphavbeta6 integrin receptor. The novel compounds can be used, in particular, as medicaments.
Bibliography:Application Number: MX2003PA08215