COMBINATIONS OF A GLP1R AGONIST AND METFORMIN AND USE THEREOF FOR THE TREATMENT OF TYPE 2 DIABETES AND OTHER DISORDERS

The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that compr...

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Main Authors James C. QUADA, JR, Stephen Thomas DAVIS, Thomas Scott YOKUM, Adnan M.M. MJALLI, Maria Carmen VALCARCE LOPEZ, Dharma Rao POLISETTI, Bradley Alan CLARK, Robert Carl ANDREWS
Format Patent
LanguageEnglish
Spanish
Published 19.07.2019
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Abstract The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GLP1R agonist and metformin. La presente invención proporciona usos de un agonista del receptor de péptido 1 similar a glucagón, en combinación con metformina. Los usos incluyen tratar la diabetes tipo 2, reducir la glucosa sanguínea y mejorar la efectividad terapéutica de la metformina. La invención también proporciona composiciones farmacéuticas que comprenden un agonista de GLP1R y metformina.
AbstractList The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GLP1R agonist and metformin. La presente invención proporciona usos de un agonista del receptor de péptido 1 similar a glucagón, en combinación con metformina. Los usos incluyen tratar la diabetes tipo 2, reducir la glucosa sanguínea y mejorar la efectividad terapéutica de la metformina. La invención también proporciona composiciones farmacéuticas que comprenden un agonista de GLP1R y metformina.
Author Dharma Rao POLISETTI
James C. QUADA, JR
Thomas Scott YOKUM
Bradley Alan CLARK
Robert Carl ANDREWS
Stephen Thomas DAVIS
Maria Carmen VALCARCE LOPEZ
Adnan M.M. MJALLI
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– fullname: Robert Carl ANDREWS
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DocumentTitleAlternate COMBINACIONES DE UN AGONISTA DE GLP1R Y METFORMINA, Y USO DE LOS MISMOS PARA EL TRATAMIENTO DE LA DIABETES TIPO 2 Y OTROS TRASTORNOS.
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Snippet The present invention provides uses of a glucagon-like peptide 1 receptor agonist in combination with metformin. Uses include treating type 2 diabetes,...
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SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title COMBINATIONS OF A GLP1R AGONIST AND METFORMIN AND USE THEREOF FOR THE TREATMENT OF TYPE 2 DIABETES AND OTHER DISORDERS
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