IMIDAZOPYRROLOPYRIDINE AS INHIBITORS OF THE JAK FAMILY OF KINASES

2-((1r,4r)-4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)cyclo hexyl)acetonitrile compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions mediated by JAK, such as inflammatory...

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Main Authors WANG Aihua, VENABLE Jennifer D, CHAI Wenying, BACANI Genesis M, KRAWCZUK Paul J, KREUTTER Kevin D, SEIERSTAD Mark, SMITH Russel C, LEONARD Kristi, KOUDRIAKOVA Tatiana, TICHENOR Mark S, RIZZOLIO Michele C
Format Patent
LanguageEnglish
Spanish
Published 13.10.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:2-((1r,4r)-4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)cyclo hexyl)acetonitrile compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions mediated by JAK, such as inflammatory bowel disease. Compuestos de 2-((1r,4r)-4-(imidazo[4,5-d]pirrolo[2,3-b]piridin-1( 6H)-il)ciclohexil)acetonitrilo, composiciones farmacéuticas que los contienen, métodos para elaborarlos, y métodos para usarlos que incluyen métodos para tratar enfermedades, desórdenes y condiciones mediadas por JAK, tales como la enfermedad inflamatoria del intestino.
Bibliography:Application Number: MX20210011438