THE SYNTHESIS PROCESS OF A HYDROGEL-BASED ON CHITOSAN FUNCTIONALIZED WITH CARBOXYLIC ACID AND CROSS-LINKED WITH DICARBOXYLIC ACID

• Main Authors: RODRÍGUEZ GONZÁLEZ Jorge Alberto, CAMACHO RUIZ Rosa María, OJEDA HERNÁNDEZ Doddy Denise, MATEOS DÍAZ Juan Carlos, CANALES AGUIRRE Alejandro Arturo
• Format: Patent
• Language: English; Spanish
• Published: 22.04.2022
• Subjects: AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F,C08G; CHEMISTRY; COMPOSITIONS BASED THEREON; DERIVATIVES THEREOF; GENERAL PROCESSES OF COMPOUNDING; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC MACROMOLECULAR COMPOUNDS; POLYSACCHARIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; THEIR PREPARATION OR CHEMICAL WORKING-UP; USE OF INORGANIC OR NON-MACROMOLECULAR ORGANIC SUBSTANCES ASCOMPOUNDING INGREDIENTS; WORKING-UP

The present invention relates to a process for synthesizing a hydrogel based on functionalized chitosan with a carboxylic acid. It consists of a) functionalizing chitosan with hydroxycinnamic acid, b) recovering the functionalized chitosan, c) crosslinking it with a dicarboxylic acid, and d) recovering hydrogel based on chitosan with hydroxycinnamic acid and cross-linked with a dicarboxylic acid. Un proceso de síntesis de un hidrogel a base de quitosano funcionalizado con ácido carboxílico, que comprende las siguientes etapas: a) funcionalizar quitosano con ácido hidroxicinámico, b) recuperar del quitosano funcionalizado, c) llevar a cabo entrecruzamiento con ácido dicarboxílico del quitosano funcionalizado, y d) recuperar hidrogel a base de quitosano funcionalizado con ácido hidroxicinámico y entrecruzado con ácido dicarboxílico.