TLR7 AGONIST CRYSTALLINE FORM A, PREPARATION METHOD AND USE THEREOF

• Main Authors: Zheng WANG, Yilong ZHOU, Fei SUN, Rui ZHAO, Zhaozhong DING, Ling YANG, Yinghu HU
• Format: Patent
• Language: English; Spanish
• Published: 11.12.2018
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to crystalline form A of a TLR7 agonist 2-butoxy-7-(4-(pyrrolidin-1-ylmethyl)-benzyl)-5H-pyrrolo[3,2-d] pyrimidin-4-amine (formula I), a method for preparing the crystalline form A, and the use thereof. La presente invencion se refiere a una forma cristalina A de un ago...