NON-AGGLOMERATING BIOCONJUGATES OF AMYLIN-MIMETIC COMPOUNDS AND POLYETHYLENEGLYCOL

• Main Authors: Mariana FERNANDES DE AVILA NETTO GUTERRES, Luis Mauricio TRAMBAIOLI DA ROCHA E LIMA, Luiz Henrique GUERREIRO ROSADO, Bruno MELO VIEIRA GONÇALVES FERREIRA
• Format: Patent
• Language: English; Spanish
• Published: 20.12.2016
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention generally concerns new non-agglomerating bioconjugates of amylin-mimetic compounds with polyethylene glycol, and their use mainly in the treatment of diseases associated with extracellular amyloid deposition or accumulation that contributes to the dysfunction or failure of syst...