DIHYDROPYRIDAZINE-3,5-DIONE DERIVATIVE

• Main Authors: HORI, NOBUYUKI, HORIBA, NAOSHI, HARADA, TAKEO, KASWIWAGI, HIROTAKA, MURATA, YOSHIHISA, ONO, YOSHIYUKI, OHTOMO, SHUICHI, OKAMOTO, NAOKI, TACHIBANA, KAZUTAKA, IDE, MITSUAKI, MIZUGUCHI, EISAKU, ICHIDA, YASUHIRO, OHTAKE, YOSHIHITO, KIMBARA, ATSUSHI, NOMURA, KENICHI, TANAKA, SHOTA
• Format: Patent
• Language: English; Spanish
• Published: 10.02.2016
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

According to the present invention, provided are a dihydropyridazine-3,5-dione derivative, a salt thereof, and solvates of the derivative and of the salt. Also provided are the following that contain any of said compounds as an active ingredient: a drug, a drug composition, a sodium-dependent phosphate transporter inhibitor, and a prophylactic and/or therapeutic agent as well as a prophylactic and/or therapeutic method for hyperphosphatemia, secondary hyperparathyroidism, and chronic renal failure. La presente invención proporciona un derivado de dihidropiridazin-3,5-diona o una sal del mismo, o un solvato del compuesto o la sal, un fármaco farmacéutico, una composición farmacéutica, un inhibidor del transportador de fosfato dependiente de sodio y un agente de prevención y/o terapéutico para la hiperfosfatemia, hiperparatiroidismo secundario, e insuficiencia renal crónica, que comprende el compuesto como un ingrediente activo, y un método para la prevención y/o tratamiento.