BINDING MOLECULES FOR BCMA AND CD3

• Main Authors: RALF LUTTERBUESE, BARBARA HEBEIS, PATRICK HOFFMANN, PETER KUFER, TOBIAS RAUM, DORIS RAU, SUSANNE HIPP, PAUL ADAM, ERIC BORGES, ROMAN KISCHEL
• Format: Patent
• Language: English; Spanish
• Published: 22.09.2014
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The present invention relates to a binding molecule which is at least bispecific comprising a first and a second binding domain,wherein the first binding domain is capable of binding to epitope cluster3 of BCMA,and the second binding domain is capable of binding to the Tcell CD3 receptor complex. Mo...