COMPOUNDS AND COMPOSITIONS AS c-KIT KINASE INHIBITORS

• Main Authors: JON LOREN, BAO NGUYEN, HANK MICHAEL JAMES PETRASSI, XIAOLIN LI, VALENTINA MOLTENI, JULIET NABAKKA, VINCE YEH, XIAODONG LIU
• Format: Patent
• Language: English; Spanish
• Published: 25.11.2014
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

The invention provides compounds of formulae (I) and (II) and pharmaceutical compositions thereof, which are useful as protein kinase inhibitors, as well as methods for using such compounds to treat, ameliorate or prevent a condition associated with abnormal or deregulated kinase activity. In some e...