NOVEL TRICYCLIC COMPOUNDS

• Main Authors: DAWN M. GEORGE, BRYAN A. FIAMENGO, NEIL WISHART, DAVID J. CALDERWOOD, ERIC C. BREINLINGER, LU WANG, MICHAEL FRIEDMAN, ANNA M. ERICSSON, KELLY D. MULLEN, JEFFREY W. VOSS, ERIC R. GOEDKEN, GRIER A. WALLACE, GAGANDEEP SOMAL, MARIA A. ARGIRIADI, KENT D. STEWART, BIQIN C. LI, KRISTINE E. FRANK, NATHAN S. JOSEPHSOHN, MICHAEL J. MORYTKO, KEVIN R. WOLLER
• Format: Patent
• Language: English; Spanish
• Published: 19.06.2012
• Subjects: AGRICULTURE; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; TRAPPING

The invention provides a compound of Formula (Ia), (Ib), (Ic), (Id), (Ie), (If), (Ig), (Ih), (Ii), (Ij), (Ik), or (Il) as defined herein, pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions. La invención proporciona un compuesto de Fórmula (la), (Ib), (Ic), (Id), (le), (If), (lg), (Ih), (Ii), (lj), (1k), o (II) como se define en la presente, sales farmacéuticamente aceptables, profármacos, metabilitos biológicamente activos, estereoisómeros e isómeros de los mismos en donde las variables son como se define en la presente. Los compuestos de la invención son útiles para tratar condiciones inmunológicas y oncológicas.