TRIAZOLOPYRIDINES AS PHOSPHODIESTERASE INHIBITORS FOR TREATMENT OF DERMAL DISEASES

The present invention relates to a compound according to formula I, wherein R1, R2 and A are as defined herein, which exhibit PDE4 inhibitory activity and may be used in the treatment of inflammatory diseases or autoimmune diseases, in particular inflammatory or proliferative dermal diseases. La pre...

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Bibliographic Details
Main Authors ANNE MARIE HORNEMAN, THOMAS VIFIAN, SIMON FELDBAEK NIELSEN, JESPER FAERGEMANN LAU
Format Patent
LanguageEnglish
Spanish
Published 28.07.2011
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to a compound according to formula I, wherein R1, R2 and A are as defined herein, which exhibit PDE4 inhibitory activity and may be used in the treatment of inflammatory diseases or autoimmune diseases, in particular inflammatory or proliferative dermal diseases. La presente invención se refiere a un compuesto de conformidad con la fórmula I, en donde R1, R2 y A son como se definen en la presente, el cual exhibe actividad inhibitoria de PDE4 y se pueden usar en el tratamiento de enfermedades inflamatorias o enfermedades autoinmunes, en particular enfermedades dérmicas inflamatorias o proliferativas. (Ver fórmula (I)).
Bibliography:Application Number: MX20110006428