PRIMARY CARBOXAMIDES AS BTK INHIBITORS

• Main Authors: FRANK, Kristine E, BONAFOUX, Dominique, OSUMA, Augustine, HUNTLEY, Raymond, VASUDEVAN, Anil, DAVIS, Heather M, HEROLD, J. Martin, HOEMANN, Michael Z, VAN CAMP, Jennifer, WILSON, Noel S, FRIEDMAN, Michael M, SHEPPARD, George, VAN EPPS, Stacy A, SOMAL, Gagandeep K, XU, Xiangdong, WALLACE, Grier A, WANG, Lu, WANG, Zhi
• Format: Patent
• Language: English; French; German
• Published: 20.10.2019
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; METALLURGY; ORGANIC CHEMISTRY

The invention provides compounds of Formula (I)pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.