Pyrrolo[2,3-d]pyrimidine derivatives as inhibitors of Janus-related Kinases (JAK)

The invention relates to pharmaceutically active pyrollo[2,3-d]pyrimidine derivatives.According to the invention, claimed are pyrrolo[2,3-d]pyrimidine derivatives of Formula IA:Also, claimed is their use as Janus Kinase (JAK) inhibitors and pharmaceutical compositions containing them. Invenţia se re...

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Bibliographic Details
Main Authors TENBRINK Ruth E, UNWALLA Rayomand Jal, BROWN Matthew Frank, KAILA Neelu, FENWICK Ashley Edward, MITTON-FRY Mark J, PARIKH Mihir D, FLANAGAN Mark Edward, JOHNSON Timothy Allan, STROHBACH Joseph Walter, GONZALES Andrea, TRZUPEK John David, VAZQUEZ Michael L
Format Patent
LanguageEnglish
Romanian
Russian
Published 31.07.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to pharmaceutically active pyrollo[2,3-d]pyrimidine derivatives.According to the invention, claimed are pyrrolo[2,3-d]pyrimidine derivatives of Formula IA:Also, claimed is their use as Janus Kinase (JAK) inhibitors and pharmaceutical compositions containing them. Invenţia se referă la derivaţi ai pirolo[2,3-d]pirimidinei farmaceutic activi. Conform invenţiei, se revendică derivaţi ai pirolo[2,3-d]pirimidinei cu formula IA: De asemenea, se revendică utilizarea lor în calitate de inhibitori de Kinaze Janus (JAK) şi compoziţii farmaceutice care îi conţin. Изобретение относится к фармацевтически активным производным пиролло[2,3-d]пиримидина.Согласно изобретению, заявляются производные пиролло[2,3-d]пиримидина с формулой IA: Также, заявляется их применение в качестве ингибиторов Янус Киназ (JAK) и содержащие их фармацевтические композиции.
Bibliography:Application Number: MD20150000073