N-carbamimidoyl-2-((8aS)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-yl)acetamide compound with antiproliferative and cytotoxic properties

• Main Authors: ARÎCU Aculina, UNGUR Nicon, SECARA Elena, BARBA Alic, KUCHKOVA Kaleria, DRAGALIN Ion, DUCA Gheorghe
• Format: Patent
• Language: English; Romanian; Russian
• Published: 31.05.2019
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES

The invention relates to chemistry and medicine, in particular to a compound with hybrid terpene-guanidine skeleton and can be used for treating cancer.Summary of the invention consists in that the compound N-carbamimidoyl-2-((8aS)-2,5,5,8a-tetramethyl-3,4,4a,5,6,7,8,8a-octahydronaphthalene-1-yl)acetamide is claimed for use as a compound with antiproliferative and cytotoxic properties. Invenţia se referă la chimie şi medicină, în special la un compus cu schelet hibrid terpenic şi guanidinic şi poate fi utilizat pentru tramentul cancerului.Esenţa invenţiei constă în aceea că se revendică compusul N-carbamimidoil-2-((8aS)-2,5,5, 8a-tetrametil-3,4,4a,5,6,7,8,8a-octahidronaftalen-1-il)acetamidă pentru utilizare în calitate de compus cu activitate antiproliferativă şi citotoxică. Изобретение относится к химии и медицине, в частности к соединению с гибридным терпеново-гуанидиновым скелетом и может быть использовано для лечения рака.Сущность изобретения состоит в том, что заявляется соединение N-карбамимидоил-2-((8aS)-2,5,5,8a-тетраметил-3,4,4a,5,6,7,8,8a-октагидронафталин-1-ил)ацетамид для использования в качестве соединения с антипролиферативными и цитотоксическими свойствами.