3-ARYL-5-ALKYLTHIO-4H-1,2,4-TRIAZOLES

Compounds of the formula or a pharmaceutically acceptable salts thereof, wherein Ar is phenyl, naphthyl, or a monocylic heteroaryl moiety selected from thienyl, pyridyl, pyrrolyl, and N-(C1-6 lower alkyl)pyrrolyl; R1 is C1-6 alkyl; R2 is hydrogen or C1-6 alkyl; R is C1-6 alkyl, C1-6 alkoxy, hydroxy,...

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Bibliographic Details
Main Authors KANE, JOHN M, MILLER, FRANCIS P
Format Patent
LanguageEnglish
Korean
Published 29.05.1996
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of the formula or a pharmaceutically acceptable salts thereof, wherein Ar is phenyl, naphthyl, or a monocylic heteroaryl moiety selected from thienyl, pyridyl, pyrrolyl, and N-(C1-6 lower alkyl)pyrrolyl; R1 is C1-6 alkyl; R2 is hydrogen or C1-6 alkyl; R is C1-6 alkyl, C1-6 alkoxy, hydroxy, halogeno or trifluoromethyl and n is zero, 1 or 2, or Rn-(Ar) is methylenedioxyphenyl; and each of m and q is zero, 1 or 2 are useful as muscle relaxants, spasmolytics, anticonvulsants and anxiolytics.
Bibliography:Application Number: KR19880000562