METHOD OF PREPARING FOR PYRIDINE

A process for preparing pyridine derics. of formula (I) comprises (a) reacting 3,5-dimethyl pyridine-N-oxide of formula (II) with a halogenating agent to obtain 3,5-dimethyl-4-chloro pyridine of formula (III), and (b) reacting (III) with an oxidizing agent and a base. Pref. the halogenating agent is...

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Bibliographic Details
Main Authors MUN, YONG - HO, MUN, SUN - KU, LEE, KWAN - SUN
Format Patent
LanguageEnglish
Korean
Published 29.08.1992
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:A process for preparing pyridine derics. of formula (I) comprises (a) reacting 3,5-dimethyl pyridine-N-oxide of formula (II) with a halogenating agent to obtain 3,5-dimethyl-4-chloro pyridine of formula (III), and (b) reacting (III) with an oxidizing agent and a base. Pref. the halogenating agent is POCl3; the oxidizing agent is H2O2; the base is potassium methoxide. Cpds. (I) are intermediates in the prepn. of omeprazole which is useful as an antiulcer drug.
Bibliography:Application Number: KR19920010695