PROCESS FOR THE PREPARATION OF 4,5,6,7-TETRAHYDRO THIAZOLO (5,4-C) PYRIDINE DERIVATIVES

• Main Authors: VAGHI FABRIZIO, SCARPONI UGO, LAZZARINI ANNA M, CASTELLO RENATO, TOTI DANIELA, CESERANI ROBERTO, CASTIGLIONE ROBERTONE
• Format: Patent
• Language: English; Korean
• Published: 05.11.1991
• Edition: 5
• Subjects: CHEMISTRY; HETEROCYCLIC COMPOUNDS; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

A compound of formula I: wherein either (i) each of R1 and R2 independently represents a hydrogen atom or an organic group, or (ii) R1 and R2 linked together form a heterocyclic ring or (iii) R2 is hydrogen and R1 is wherein each of R6 and R7 independently represents hydrogen or an organic group, n is 0-3, X is O, S, NH, NR8, CHNO2 or CHSO2R4, wherein R8 and R4 are organic groups and R3 represents an organic group. The compound of formula I is effective as an anti-ulcer agent and is highly effective as a histamine H2-receptor antagonist.