STING 작용제로서 융합된 헤테로아릴 히드록사메이트
본 발명은 화학식 I로 나타낸 신규한 치환된 이종환식 화합물, 또는 이들의 약제학적으로 허용가능한 염, 용매화물, 다형체, 에스테르, 호변이성질체 또는 전구약물, 및 이러한 화합물을 포함하는 조성물을 제공한다. 제공된 화합물은 인터페론 유전자의 자극제(STING)의작용제로서 사용될 수있으며, 암 및 특정한 감염성 질환의 치료에 유용하다. [화학식 I] JPEGpct00100.jpg6352 The invention provides novel substituted heterocyclic compounds represented by th...
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Format | Patent |
Language | Korean |
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25.07.2024
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Abstract | 본 발명은 화학식 I로 나타낸 신규한 치환된 이종환식 화합물, 또는 이들의 약제학적으로 허용가능한 염, 용매화물, 다형체, 에스테르, 호변이성질체 또는 전구약물, 및 이러한 화합물을 포함하는 조성물을 제공한다. 제공된 화합물은 인터페론 유전자의 자극제(STING)의작용제로서 사용될 수있으며, 암 및 특정한 감염성 질환의 치료에 유용하다. [화학식 I] JPEGpct00100.jpg6352
The invention provides novel substituted heterocyclic compounds represented by the Formulas I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as agonists of Stimulator of Interferon Genes (STING) and are useful in the treatment of cancers and certain infectious diseases. |
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AbstractList | 본 발명은 화학식 I로 나타낸 신규한 치환된 이종환식 화합물, 또는 이들의 약제학적으로 허용가능한 염, 용매화물, 다형체, 에스테르, 호변이성질체 또는 전구약물, 및 이러한 화합물을 포함하는 조성물을 제공한다. 제공된 화합물은 인터페론 유전자의 자극제(STING)의작용제로서 사용될 수있으며, 암 및 특정한 감염성 질환의 치료에 유용하다. [화학식 I] JPEGpct00100.jpg6352
The invention provides novel substituted heterocyclic compounds represented by the Formulas I, or a pharmaceutically acceptable salt, solvate, polymorph, ester, tautomer or prodrug thereof, and a composition comprising these compounds. The compounds provided can be used as agonists of Stimulator of Interferon Genes (STING) and are useful in the treatment of cancers and certain infectious diseases. |
Author | YANG INHO KIM SUNJOO JEON SUNHWA LEE JUNGWOO LEE JINWOO SEO JEONGBEOB HAN CHEOLKYU YOON CHEOLHWAN SHIN YOUNGDO JEON SEEUN KANG HONGJUN KANG BYUNGNAM |
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Snippet | 본 발명은 화학식 I로 나타낸 신규한 치환된 이종환식 화합물, 또는 이들의 약제학적으로 허용가능한 염, 용매화물, 다형체, 에스테르, 호변이성질체 또는 전구약물, 및 이러한 화합물을 포함하는 조성물을 제공한다. 제공된 화합물은 인터페론 유전자의 자극제(STING)의작용제로서 사용될... |
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Title | STING 작용제로서 융합된 헤테로아릴 히드록사메이트 |
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