인터루킨 1 알파에 특이적인 실제 인간 항체

완전 인간 단일클론 항체(fully human monoclonal Ab)는 (i) IL-1α에 대해 매우 높은 결합 친화성(binding affinity)을 나타내는 항원-결합 가변 영역(antigen-binding variable region) 및 (ii) C1q 결합, 및 수 개의 상이한 Fc 수용체에 대한 결합을 통해 보체계(complement system)를 둘 다 활성화시키는데 효과적인 불변 영역(constant region)을 포함한다. Fully human monoclonal Abs includes (i) an anti...

Full description

Saved in:
Bibliographic Details
Main Authors SHIVASWAMY SUSHMA, SIMARD JOHN, KUZMICHEVA GALINA
Format Patent
LanguageKorean
Published 08.06.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

Abstract 완전 인간 단일클론 항체(fully human monoclonal Ab)는 (i) IL-1α에 대해 매우 높은 결합 친화성(binding affinity)을 나타내는 항원-결합 가변 영역(antigen-binding variable region) 및 (ii) C1q 결합, 및 수 개의 상이한 Fc 수용체에 대한 결합을 통해 보체계(complement system)를 둘 다 활성화시키는데 효과적인 불변 영역(constant region)을 포함한다. Fully human monoclonal Abs includes (i) an antigen-binding variable region that exhibits very high binding affinity for IL-1α and (ii) a constant region that is effective at both activating the complement system though C1q binding and binding to several different Fc receptors.
AbstractList 완전 인간 단일클론 항체(fully human monoclonal Ab)는 (i) IL-1α에 대해 매우 높은 결합 친화성(binding affinity)을 나타내는 항원-결합 가변 영역(antigen-binding variable region) 및 (ii) C1q 결합, 및 수 개의 상이한 Fc 수용체에 대한 결합을 통해 보체계(complement system)를 둘 다 활성화시키는데 효과적인 불변 영역(constant region)을 포함한다. Fully human monoclonal Abs includes (i) an antigen-binding variable region that exhibits very high binding affinity for IL-1α and (ii) a constant region that is effective at both activating the complement system though C1q binding and binding to several different Fc receptors.
Author SHIVASWAMY SUSHMA
SIMARD JOHN
KUZMICHEVA GALINA
Author_xml – fullname: SHIVASWAMY SUSHMA
– fullname: SIMARD JOHN
– fullname: KUZMICHEVA GALINA
BookMark eNrjYmDJy89L5WSwejN3x9uWDa8Xr3jbtELBUOHN1J63PT1vpk9QeNu1883cLW8WNAJVKLzpXvJmwRwFIPPVhhaFt1PXvtm0hYeBNS0xpziVF0pzMyi7uYY4e-imFuTHpxYXJCan5qWWxHsHGRkYGRsYWBiZGVk4GhOnCgC2KEFg
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
ExternalDocumentID KR20230082628A
GroupedDBID EVB
ID FETCH-epo_espacenet_KR20230082628A3
IEDL.DBID EVB
IngestDate Fri Aug 16 05:46:32 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language Korean
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_KR20230082628A3
Notes Application Number: KR20237012354
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230608&DB=EPODOC&CC=KR&NR=20230082628A
ParticipantIDs epo_espacenet_KR20230082628A
PublicationCentury 2000
PublicationDate 20230608
PublicationDateYYYYMMDD 2023-06-08
PublicationDate_xml – month: 06
  year: 2023
  text: 20230608
  day: 08
PublicationDecade 2020
PublicationYear 2023
RelatedCompanies XBIOTECH INC
RelatedCompanies_xml – name: XBIOTECH INC
Score 3.4498894
Snippet 완전 인간 단일클론 항체(fully human monoclonal Ab)는 (i) IL-1α에 대해 매우 높은 결합 친화성(binding affinity)을 나타내는 항원-결합 가변 영역(antigen-binding variable region) 및 (ii) C1q 결합, 및 수 개의...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title 인터루킨 1 알파에 특이적인 실제 인간 항체
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230608&DB=EPODOC&locale=&CC=KR&NR=20230082628A
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMbNINTNJTDLQBbYNzHVNzI3NdC1NQOfeGqaapBmmJqelGII2J_v6mXmEmnhFmEYwMeTA9sKAzwktBx-OCMxRycD8XgIurwsQg1gu4LWVxfpJmUChfHu3EFsXNWjvGNSeNrBQc3GydQ3wd_F3VnN2tvUOUvMLgsgBqzszIwtHZgZWUEMadNK-a5gTaF9KAXKl4ibIwBYANC-vRIiBKTtfmIHTGXb3mjADhy90yhvIhOa-YhEGqzdzd7xt2fB68Yq3TSsUDBXeTO1529PzZvoEhbddO9_M3fJmQSNQhcKb7iVvFsxRADJfbWhReDt17ZtNW0QZlN1cQ5w9dIGOiIf7Od47CNnFxmIMLHn5eakSDAqWFilJacmGKeZpaWkmSSlJlmZJZkYphmaWpsYmqamm5pIMMvhMksIvLc3ABeKC10JZyDCwlBSVpsoCa92SJDlwYAEAchaVng
link.rule.ids 230,309,786,891,25594,76903
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMbNINTNJTDLQBbYNzHVNzI3NdC1NQOfeGqaapBmmJqelGII2J_v6mXmEmnhFmEYwMeTA9sKAzwktBx-OCMxRycD8XgIurwsQg1gu4LWVxfpJmUChfHu3EFsXNWjvGNSeNrBQc3GydQ3wd_F3VnN2tvUOUvMLgsgBqzszIwtHZgZWc2CnENxZCnMC7UspQK5U3AQZ2AKA5uWVCDEwZecLM3A6w-5eE2bg8IVOeQOZ0NxXLMJg9WbujrctG14vXvG2aYWCocKbqT1ve3reTJ-g8LZr55u5W94saASqUHjTveTNgjkKQOarDS0Kb6eufbNpiyiDsptriLOHLtAR8XA_x3sHIbvYWIyBJS8_L1WCQcHSIiUpLdkwxTwtLc0kKSXJ0izJzCjF0MzS1NgkNdXUXJJBBp9JUvil5Rk4PUJ8feJ9PP28pRm4QFLgdVEWMgwsJUWlqbLAGrgkSQ4ccACWh5iI
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=%EC%9D%B8%ED%84%B0%EB%A3%A8%ED%82%A8+1+%EC%95%8C%ED%8C%8C%EC%97%90+%ED%8A%B9%EC%9D%B4%EC%A0%81%EC%9D%B8+%EC%8B%A4%EC%A0%9C+%EC%9D%B8%EA%B0%84+%ED%95%AD%EC%B2%B4&rft.inventor=SHIVASWAMY+SUSHMA&rft.inventor=SIMARD+JOHN&rft.inventor=KUZMICHEVA+GALINA&rft.date=2023-06-08&rft.externalDBID=A&rft.externalDocID=KR20230082628A