MLL1-WDR5 Small-Molecule Modulators of MLL1-WDR5 Interactions and the use

The present invention relates to an anti-cancer pharmaceutical composition containing a double-ring low molecule derivative as an active ingredient, and a method for manufacturing the same. The composition containing the double-ring derivative as the active ingredient can be usefully used as a compo...

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Main Authors HA HYUNG HO, KIM HYUNJOO, CHOI JONG YUN, LEE BIT, YANG HONG JU, TAE HYUN SEOP, LEE MIJIN, KIM YUNLAN
Format Patent
LanguageEnglish
Korean
Published 24.05.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to an anti-cancer pharmaceutical composition containing a double-ring low molecule derivative as an active ingredient, and a method for manufacturing the same. The composition containing the double-ring derivative as the active ingredient can be usefully used as a composition for preventing or treating cancer. The present invention relates to a compound of chemical formula 1 consisting of a double ring low molecular weight compound, or an enantiomer, diastereomer, stereoisomer, hydrate, solvate, prodrug or pharmaceutically acceptable salt thereof. 본 발명은 이중고리 저분자 유도체를 유효성분으로 함유하는 항암용 약학적 조성물 및 이의 제조방법에 관한 것으로, 상기 이중고리 유도체를 유효성분으로 함유하는 조성물은 암 예방 또는 치료용 조성물로 유용하게 사용가능하다.
Bibliography:Application Number: KR20220152080