항-BCMA 항체-약물 컨쥬게이트 및 이용 방법

BCMA에 결합하는 항체, 항원-결합 단편 및 컨쥬게이트(예를 들어, 항체-약물 컨쥬게이트(ADC), 예컨대 스플라이싱 조절제를 포함하는 것들)가 개시된다. 본 개시내용은 추가로 본원에 제공되는 조성물을 투여함으로써 암의 치료에 사용하기 위한 방법 및 조성물에 관한 것이다. Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that b...

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Main Authors PAZOLLI ERMIRA, ALMAGRO JUAN C, HENRY RYAN, ZHU PING, PALACINO JAMES, SAMARAKOON THIWANKA, FISHKIN NATHAN
Format Patent
LanguageKorean
Published 10.02.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

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Abstract BCMA에 결합하는 항체, 항원-결합 단편 및 컨쥬게이트(예를 들어, 항체-약물 컨쥬게이트(ADC), 예컨대 스플라이싱 조절제를 포함하는 것들)가 개시된다. 본 개시내용은 추가로 본원에 제공되는 조성물을 투여함으로써 암의 치료에 사용하기 위한 방법 및 조성물에 관한 것이다. Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.
AbstractList BCMA에 결합하는 항체, 항원-결합 단편 및 컨쥬게이트(예를 들어, 항체-약물 컨쥬게이트(ADC), 예컨대 스플라이싱 조절제를 포함하는 것들)가 개시된다. 본 개시내용은 추가로 본원에 제공되는 조성물을 투여함으로써 암의 치료에 사용하기 위한 방법 및 조성물에 관한 것이다. Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.
Author FISHKIN NATHAN
HENRY RYAN
ALMAGRO JUAN C
PALACINO JAMES
SAMARAKOON THIWANKA
ZHU PING
PAZOLLI ERMIRA
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– fullname: SAMARAKOON THIWANKA
– fullname: FISHKIN NATHAN
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Snippet BCMA에 결합하는 항체, 항원-결합 단편 및 컨쥬게이트(예를 들어, 항체-약물 컨쥬게이트(ADC), 예컨대 스플라이싱 조절제를 포함하는 것들)가 개시된다. 본 개시내용은 추가로 본원에 제공되는 조성물을 투여함으로써 암의 치료에 사용하기 위한 방법 및 조성물에 관한 것이다....
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title 항-BCMA 항체-약물 컨쥬게이트 및 이용 방법
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