TIGIT에 대한 항체

본 개시내용은 TIGIT에 특이적으로 결합하는 항체를 제공한다. 항체는 CD155에 대한 TIGIT의 결합을 억제함으로써 T 세포 및 자연 살해 세포의 실질적인 활성화를 위한 능력을 갖는다. 항체는 다른 응용 중에서도 암 및 감염성 질환의 치료에 사용될 수 있다. The present disclosure provides antibodies that specifically bind to TIGIT. The antibodies have the capacity for substantial activation of T cells and n...

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Main Authors WALKER NIGEL PELHAM CLINTON, LIPPINCOTT JOHN, GAUTHIER KELSEY SIVICK, ZHAO XIAONING
Format Patent
LanguageKorean
Published 07.02.2023
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract 본 개시내용은 TIGIT에 특이적으로 결합하는 항체를 제공한다. 항체는 CD155에 대한 TIGIT의 결합을 억제함으로써 T 세포 및 자연 살해 세포의 실질적인 활성화를 위한 능력을 갖는다. 항체는 다른 응용 중에서도 암 및 감염성 질환의 치료에 사용될 수 있다. The present disclosure provides antibodies that specifically bind to TIGIT. The antibodies have the capacity for substantial activation of T cells and natural killer cells by inhibiting binding of TIGIT to CD155. The antibodies can be used for treatment of cancer and infectious disease, among other applications.
AbstractList 본 개시내용은 TIGIT에 특이적으로 결합하는 항체를 제공한다. 항체는 CD155에 대한 TIGIT의 결합을 억제함으로써 T 세포 및 자연 살해 세포의 실질적인 활성화를 위한 능력을 갖는다. 항체는 다른 응용 중에서도 암 및 감염성 질환의 치료에 사용될 수 있다. The present disclosure provides antibodies that specifically bind to TIGIT. The antibodies have the capacity for substantial activation of T cells and natural killer cells by inhibiting binding of TIGIT to CD155. The antibodies can be used for treatment of cancer and infectious disease, among other applications.
Author ZHAO XIAONING
LIPPINCOTT JOHN
GAUTHIER KELSEY SIVICK
WALKER NIGEL PELHAM CLINTON
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Snippet 본 개시내용은 TIGIT에 특이적으로 결합하는 항체를 제공한다. 항체는 CD155에 대한 TIGIT의 결합을 억제함으로써 T 세포 및 자연 살해 세포의 실질적인 활성화를 위한 능력을 갖는다. 항체는 다른 응용 중에서도 암 및 감염성 질환의 치료에 사용될 수 있다. The present...
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title TIGIT에 대한 항체
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