4D USE OF SEMAPHORIN-4D BINDING MOLECULES FOR TREATING NEURODEGENERATIVE DISORDERS

• Main Authors: BOWERS WILLIAM J, SMITH ERNEST S, ZAUDERER MAURICE, JONASON ALAN
• Format: Patent
• Language: English; Korean
• Published: 09.08.2022
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

본 발명에서는, 세마포린-4D(SEMA4D)에 또는 그의 플렉신-B1 또는 플렉신-B2 수용체에 특이적으로 결합하는 단리된 결합 분자의 유효량을 신경퇴행성 장애를 갖는 대상에게 투여하는 것을 포함하는, 상기대상에서 증상을 완화하는 방법이 제공된다. Provided herein are methods for alleviating symptoms in a subject having a neurodegenerative disorder, comprising administering to the subject an effective amoun...