새로운 4-1BBL 삼량체-함유 항원 결합 분자

본 발명은 PD-L1에 특이적으로 결합할 수 있는 적어도 하나의 항원 결합 도메인을 포함하는 4-1BBL 삼량체-함유 항원 결합 분자 및 이의 암 치료에서의 용도에 관한 것이다. The invention relates to 4-1BBL trimer-containing antigen binding molecules comprising at least one antigen binding domain capable of specific binding to PD-L1 and their use in the treatment of cancer...

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Main Authors FERRARA KOLLER CLAUDIA, KLEIN CHRISTIAN, UMANA PABLO, CLAUS CHRISTINA
Format Patent
LanguageKorean
Published 02.08.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Abstract 본 발명은 PD-L1에 특이적으로 결합할 수 있는 적어도 하나의 항원 결합 도메인을 포함하는 4-1BBL 삼량체-함유 항원 결합 분자 및 이의 암 치료에서의 용도에 관한 것이다. The invention relates to 4-1BBL trimer-containing antigen binding molecules comprising at least one antigen binding domain capable of specific binding to PD-L1 and their use in the treatment of cancer.
AbstractList 본 발명은 PD-L1에 특이적으로 결합할 수 있는 적어도 하나의 항원 결합 도메인을 포함하는 4-1BBL 삼량체-함유 항원 결합 분자 및 이의 암 치료에서의 용도에 관한 것이다. The invention relates to 4-1BBL trimer-containing antigen binding molecules comprising at least one antigen binding domain capable of specific binding to PD-L1 and their use in the treatment of cancer.
Author CLAUS CHRISTINA
UMANA PABLO
FERRARA KOLLER CLAUDIA
KLEIN CHRISTIAN
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Snippet 본 발명은 PD-L1에 특이적으로 결합할 수 있는 적어도 하나의 항원 결합 도메인을 포함하는 4-1BBL 삼량체-함유 항원 결합 분자 및 이의 암 치료에서의 용도에 관한 것이다. The invention relates to 4-1BBL trimer-containing antigen...
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title 새로운 4-1BBL 삼량체-함유 항원 결합 분자
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