BLA-9 K Lactobacillus acidophilus BLA-9 with biological conversion activity of saponin a method of preparation for fermented red ginseng extracts having increased content of ginsenoside compound K using the same fermented red ginseng extracts using thereby and health-functional food composition containing the same

• Main Authors: MOON JOO MYUNG, KIM YOON HEE, OH TAE KYU, KIM TAE YOUNG
• Format: Patent
• Language: English; Korean
• Published: 12.04.2022
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; FOODS OR FOODSTUFFS; FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J; HUMAN NECESSITIES; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL; PROCESSES USING MICROORGANISMS; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES; VINEGAR; WINE

The present invention is a Lactobacillus acidophilus BLA-9 strain having bioconversion ability for saponin, a method for preparing a fermented red ginseng extract with an increased content of compound K using the same, a fermented red ginseng extract thereby, and a health functional food composition including the same. The Lactobacillus acidophilus BLA-9 strain (accession number: KCTC18848P) having bioconversion ability to saponin has excellent ginsenoside bioconversion ability. When the strain is inoculated into a red ginseng extract and fermented, a fermented red ginseng extract having a high content of ginsenoside F2 and compound K can be obtained. In addition, according to the preparing method of the present invention, the production efficiency of the compound K is remarkably increased, and a fermented red ginseng extract with a further increased content of compound K can be obtained. Since the fermented red ginseng extract of the present invention contains a large amount of the compound K which is easily absorbed by the body, the fermented red ginseng extract is very useful as a healthy functional food or food material. 본 발명은 사포닌에 대해 생물전환능을 갖는 락토바실러스 애시도필러스 BLA-9 균주, 이를 이용한 화합물 K의 함량이 증대된 발효 홍삼 추출물의 제조 방법, 이에 따른 발효 홍삼 추출물 및 이를 포함하는 건강기능식품 조성물에 관한 것이다. 본 발명의 사포닌에 대해 생물전환능을 갖는 락토바실러스 애시도필러스(Lactobacillus acidophilus) BLA-9 균주(기탁번호: KCTC18848P)는 우수한 진세노사이드 생물전환능을 갖는다. 홍삼 추출물에 상기 균주를 접종하고 발효시키는 경우, 진세노사이드 F2 및 화합물 K의 함량이 높은 발효 홍삼 추출물을 얻을 수 있다. 또한, 본 발명의 제조 방법에 의하면 화합물 K의 생산 효율이 현저히 증대되어, 화합물 K의 함량이 더욱 증대된 발효 홍삼 추출물을 얻을 수 있다. 본 발명의 발효 홍삼 추출물은 체내 흡수가 용이한 화합물 K를 다량 함유하고 있으므로, 건강기능식품 또는 식품 소재로 매우 유용하다.