충전 니들 시스템

• Main Authors: CICHY MARCIN, NAING JUVENAL, GUERRERO CARLOS ALBERTO DIAZ
• Format: Patent
• Language: Korean
• Published: 16.07.2021
• Subjects: BABY COMFORTERS; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE; CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICALPURPOSES; CONVEYING; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; DEVICES FOR RECEIVING SPITTLE; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGINGPHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL ORADMINISTERING FORMS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; HANDLING THIN OR FILAMENTARY MATERIAL; HUMAN NECESSITIES; HYGIENE; MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGINGARTICLES OR MATERIALS; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; PACKING; PERFORMING OPERATIONS; PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL; STORING; TRANSPORTING; UNPACKING

무균 챔버(420)에서 유체 약품을 무균 분주하기 위한 충전 니들 시스템(414)은 연성 튜빙(404)를 경유하여 유체 약품 소스(401)과 소통하며, 충전 니들 허브를 통하여 연장되는 충전 니들 튜빙; 충전 니들 튜빙의 분주 말단에 배치된 충전 니들 분주 팁; 충전 니들 허브와 탈착 가능하게 맞물리고 무균 밀봉하여, 충전 분주 팁을 에워싸는 무균 밀봉된 볼륨을 형성하는 형상을 가지며 배치되는 충전 니들 시스(503'); 유체 약품의 분주를 중단한 후, 분주 팁에 잔류하는 유체 약품품의 액적(708)을 제거)할 수 있도록 연성 튜빙을 압축하도록 구성되는 유체 압력 펄스 유도 시스템(513)을 포함한다. 유체 약품을 분주하는 방법은 액적을 제거할 수 있도록 유체 압력 펄스 유도 시스템을 작동하는 단계를 포함한다. 시스템은 분주 및 액적 제거를 자동 제어하기 위한 컨트롤러를 포함할 수 있다. The present invention involves a fill needle system for aseptically dispensing a pharmaceutical fluid in an aseptic chamber comprises a fill needle tubing in fluid communication with a pharmaceutical fluid source via flexible tubing and extending through a fill needle hub; a fill needle dispensing tip disposed at a dispensing end of the fill needle tubing; a fill needle sheath shaped and arranged to removably mate with and seal aseptically to the fill needle hub to form an aseptically sealed volume enclosing the dispensing tip; and a fluid pressure pulse induction system disposed and configured to compress the flexible tubing in order to dislodge droplets of pharmaceutical fluid retained on the dispensing tip after halting dispensing of the pharmaceutical fluid. An associated method of dispensing pharmaceutical fluid comprises operating the fluid pressure pulse induction system to dislodge the droplets. The system may comprise a controller for automatically controlling the dispensing and droplet dislodging.