대장균 조성물 및 이의 사용 방법

본 발명은 대장균 리포폴리사카라이드 및 이의 접합체로부터 유래된 변형된 O-폴리사카라이드 분자를 포함하는 면역원성 조성물에 관한 것이다. 다가 백신은 상이한 대장균 혈청형에 대해 2개 이상의 1가 면역원성 조성물을 조합하여 제조할 수 있다. 한 양태에서, 변형된 O-폴리사카라이드 분자는 wzz 유전자를 포함하는 재조합 세균에 의해 생성된다. In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide mole...

Full description

Saved in:
Bibliographic Details
Main Authors CHEN WEI, GU JIANXIN, DONALD ROBERT G. K, CHORRO LAURENT OLIVER, TAKANE KAREN KIYOKO, SINGH SUDDHAM, KIM JIN HWAN, PAN ROSALIND, LOMBERK SCOTT ELLIS, RUPPEN MARK EDWARD, CHU LING, MERCHANT NISHITH, ANDERSON ANNALIESA SYBIL, KODALI SRINIVAS, PRASAD AVVARI KRISHNA, MORAN JUSTIN KEITH, LOTVIN JASON ARNOLD
Format Patent
LanguageKorean
Published 06.05.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online AccessGet full text

Cover

Abstract 본 발명은 대장균 리포폴리사카라이드 및 이의 접합체로부터 유래된 변형된 O-폴리사카라이드 분자를 포함하는 면역원성 조성물에 관한 것이다. 다가 백신은 상이한 대장균 혈청형에 대해 2개 이상의 1가 면역원성 조성물을 조합하여 제조할 수 있다. 한 양태에서, 변형된 O-폴리사카라이드 분자는 wzz 유전자를 포함하는 재조합 세균에 의해 생성된다. In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. Multivalent vaccines may be prepared by combining two or more monovalent immunogenic compositions for different E. coli serotypes. In one embodiment, the modified O-polysaccharide molecules are produced by a recombinant bacterium that includes a wzz gene.
AbstractList 본 발명은 대장균 리포폴리사카라이드 및 이의 접합체로부터 유래된 변형된 O-폴리사카라이드 분자를 포함하는 면역원성 조성물에 관한 것이다. 다가 백신은 상이한 대장균 혈청형에 대해 2개 이상의 1가 면역원성 조성물을 조합하여 제조할 수 있다. 한 양태에서, 변형된 O-폴리사카라이드 분자는 wzz 유전자를 포함하는 재조합 세균에 의해 생성된다. In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. Multivalent vaccines may be prepared by combining two or more monovalent immunogenic compositions for different E. coli serotypes. In one embodiment, the modified O-polysaccharide molecules are produced by a recombinant bacterium that includes a wzz gene.
Author CHEN WEI
MORAN JUSTIN KEITH
KODALI SRINIVAS
PRASAD AVVARI KRISHNA
CHORRO LAURENT OLIVER
CHU LING
PAN ROSALIND
LOTVIN JASON ARNOLD
GU JIANXIN
DONALD ROBERT G. K
SINGH SUDDHAM
MERCHANT NISHITH
RUPPEN MARK EDWARD
KIM JIN HWAN
LOMBERK SCOTT ELLIS
TAKANE KAREN KIYOKO
ANDERSON ANNALIESA SYBIL
Author_xml – fullname: CHEN WEI
– fullname: GU JIANXIN
– fullname: DONALD ROBERT G. K
– fullname: CHORRO LAURENT OLIVER
– fullname: TAKANE KAREN KIYOKO
– fullname: SINGH SUDDHAM
– fullname: KIM JIN HWAN
– fullname: PAN ROSALIND
– fullname: LOMBERK SCOTT ELLIS
– fullname: RUPPEN MARK EDWARD
– fullname: CHU LING
– fullname: MERCHANT NISHITH
– fullname: ANDERSON ANNALIESA SYBIL
– fullname: KODALI SRINIVAS
– fullname: PRASAD AVVARI KRISHNA
– fullname: MORAN JUSTIN KEITH
– fullname: LOTVIN JASON ARNOLD
BookMark eNrjYmDJy89L5WTQed3T8Gbe0lfbFyi8WbjhTcvG12v2KLze0K_wZu6WN3NnKLxpWvNm1kqgyMrXm6byMLCmJeYUp_JCaW4GZTfXEGcP3dSC_PjU4oLE5NS81JJ47yAjAyNDAwMTSwszM0dj4lQBALjGOLg
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
ExternalDocumentID KR20210049866A
GroupedDBID EVB
ID FETCH-epo_espacenet_KR20210049866A3
IEDL.DBID EVB
IngestDate Fri Jul 19 10:41:37 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language Korean
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_KR20210049866A3
Notes Application Number: KR20217008625
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210506&DB=EPODOC&CC=KR&NR=20210049866A
ParticipantIDs epo_espacenet_KR20210049866A
PublicationCentury 2000
PublicationDate 20210506
PublicationDateYYYYMMDD 2021-05-06
PublicationDate_xml – month: 05
  year: 2021
  text: 20210506
  day: 06
PublicationDecade 2020
PublicationYear 2021
RelatedCompanies PFIZER INC
RelatedCompanies_xml – name: PFIZER INC
Score 3.2948806
Snippet 본 발명은 대장균 리포폴리사카라이드 및 이의 접합체로부터 유래된 변형된 O-폴리사카라이드 분자를 포함하는 면역원성 조성물에 관한 것이다. 다가 백신은 상이한 대장균 혈청형에 대해 2개 이상의 1가 면역원성 조성물을 조합하여 제조할 수 있다. 한 양태에서, 변형된 O-폴리사카라이드...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title 대장균 조성물 및 이의 사용 방법
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210506&DB=EPODOC&locale=&CC=KR&NR=20210049866A
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQSTU2M08BthN0zU1SzHRNzNOSdBPBG3VTTI1BGyUtjVPBq3z9zDxCTbwiTCOYGHJge2HA54SWgw9HBOaoZGB-LwGX1wWIQSwX8NrKYv2kTKBQvr1biK2LGrR3DOy_mBqYqbk42boG-Lv4O6s5O9t6B6n5BUHkgK1hCzMzR2YGVlBDGnTSvmuYE2hfSgFypeImyMAWADQvr0SIgSk7X5iB0xl295owA4cvdMobyITmvmIRBp3XPQ1v5i19tX2BwpuFG960bHy9Zo_C6w39Cm_mbnkzd4bCm6Y1b2atBIqsfL1pqiiDsptriLOHLtDaeLgv472DkN1oLMbAAuz_p0owKCQC2wgpyWapaRbArpNpqplFsrlFSnJSKjCnplkAO4GSDDL4TJLCLy3NwAXigtfwmckwsJQUlabKAuvZkiQ5cPAAAFp6jAo
link.rule.ids 230,309,786,891,25594,76906
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQSTU2M08BthN0zU1SzHRNzNOSdBPBG3VTTI1BGyUtjVPBq3z9zDxCTbwiTCOYGHJge2HA54SWgw9HBOaoZGB-LwGX1wWIQSwX8NrKYv2kTKBQvr1biK2LGrR3DOy_mBqYqbk42boG-Lv4O6s5O9t6B6n5BUHkgK1hCzMzR2YGVnPQ-bygxlOYE2hfSgFypeImyMAWADQvr0SIgSk7X5iB0xl295owA4cvdMobyITmvmIRBp3XPQ1v5i19tX2BwpuFG960bHy9Zo_C6w39Cm_mbnkzd4bCm6Y1b2atBIqsfL1pqiiDsptriLOHLtDaeLgv472DkN1oLMbAAuz_p0owKCQC2wgpyWapaRbArpNpqplFsrlFSnJSKjCnplkAO4GSDDL4TJLCLy3PwOkR4usT7-Pp5y3NwAWSAq_nM5NhYCkpKk2VBda5JUly4KACAA_Njvc
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=%EB%8C%80%EC%9E%A5%EA%B7%A0+%EC%A1%B0%EC%84%B1%EB%AC%BC+%EB%B0%8F+%EC%9D%B4%EC%9D%98+%EC%82%AC%EC%9A%A9+%EB%B0%A9%EB%B2%95&rft.inventor=CHEN+WEI&rft.inventor=GU+JIANXIN&rft.inventor=DONALD+ROBERT+G.+K&rft.inventor=CHORRO+LAURENT+OLIVER&rft.inventor=TAKANE+KAREN+KIYOKO&rft.inventor=SINGH+SUDDHAM&rft.inventor=KIM+JIN+HWAN&rft.inventor=PAN+ROSALIND&rft.inventor=LOMBERK+SCOTT+ELLIS&rft.inventor=RUPPEN+MARK+EDWARD&rft.inventor=CHU+LING&rft.inventor=MERCHANT+NISHITH&rft.inventor=ANDERSON+ANNALIESA+SYBIL&rft.inventor=KODALI+SRINIVAS&rft.inventor=PRASAD+AVVARI+KRISHNA&rft.inventor=MORAN+JUSTIN+KEITH&rft.inventor=LOTVIN+JASON+ARNOLD&rft.date=2021-05-06&rft.externalDBID=A&rft.externalDocID=KR20210049866A