PRODRUG OF CASPASE INHIBITOR

The present invention relates to an isoxazoline derivative having an ester portion, which is a prodrug of a caspase inhibitor, and a pharmaceutical composition containing the same. The present invention has hydrophobicity, thereby being suitable for long-lasting formulation. 본 발명은 캐스파제 (Caspase) 저해제...

Full description

Saved in:
Bibliographic Details
Main Authors SONG JEONG UK, KIM JEONG AE, BAEK JAE UK, CHOI SEI HYUN, PARK AH BYEOL, PARK HYUN SEO, MOON HEE JEONG, KANG SO YEONG, KIM SUNG WON
Format Patent
LanguageEnglish
Korean
Published 09.11.2020
Subjects
Online AccessGet full text

Cover

Loading…
Abstract The present invention relates to an isoxazoline derivative having an ester portion, which is a prodrug of a caspase inhibitor, and a pharmaceutical composition containing the same. The present invention has hydrophobicity, thereby being suitable for long-lasting formulation. 본 발명은 캐스파제 (Caspase) 저해제의 프로드럭 (prodrug)인, 에스테르 부분을 가지는 이소옥사졸린 유도체 및 이를 함유하는 약제학적 조성물에 관한 것이다.
AbstractList The present invention relates to an isoxazoline derivative having an ester portion, which is a prodrug of a caspase inhibitor, and a pharmaceutical composition containing the same. The present invention has hydrophobicity, thereby being suitable for long-lasting formulation. 본 발명은 캐스파제 (Caspase) 저해제의 프로드럭 (prodrug)인, 에스테르 부분을 가지는 이소옥사졸린 유도체 및 이를 함유하는 약제학적 조성물에 관한 것이다.
Author KANG SO YEONG
SONG JEONG UK
BAEK JAE UK
MOON HEE JEONG
PARK HYUN SEO
PARK AH BYEOL
CHOI SEI HYUN
KIM SUNG WON
KIM JEONG AE
Author_xml – fullname: SONG JEONG UK
– fullname: KIM JEONG AE
– fullname: BAEK JAE UK
– fullname: CHOI SEI HYUN
– fullname: PARK AH BYEOL
– fullname: PARK HYUN SEO
– fullname: MOON HEE JEONG
– fullname: KANG SO YEONG
– fullname: KIM SUNG WON
BookMark eNrjYmDJy89L5WSQCQjydwkKdVfwd1NwdgwOcAx2VfD08_B08gzxD-JhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHeQUYGRgYGhkZmlkYWjsbEqQIAymcjXQ
ContentType Patent
DBID EVB
DatabaseName esp@cenet
DatabaseTitleList
Database_xml – sequence: 1
  dbid: EVB
  name: esp@cenet
  url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP
  sourceTypes: Open Access Repository
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Chemistry
Sciences
DocumentTitleAlternate 캐스파제 저해제의 프로드럭
ExternalDocumentID KR20200126928A
GroupedDBID EVB
ID FETCH-epo_espacenet_KR20200126928A3
IEDL.DBID EVB
IngestDate Fri Jul 19 12:57:21 EDT 2024
IsOpenAccess true
IsPeerReviewed false
IsScholarly false
Language English
Korean
LinkModel DirectLink
MergedId FETCHMERGED-epo_espacenet_KR20200126928A3
Notes Application Number: KR20200052177
OpenAccessLink https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201109&DB=EPODOC&CC=KR&NR=20200126928A
ParticipantIDs epo_espacenet_KR20200126928A
PublicationCentury 2000
PublicationDate 20201109
PublicationDateYYYYMMDD 2020-11-09
PublicationDate_xml – month: 11
  year: 2020
  text: 20201109
  day: 09
PublicationDecade 2020
PublicationYear 2020
RelatedCompanies LG CHEM, LTD
RelatedCompanies_xml – name: LG CHEM, LTD
Score 3.277561
Snippet The present invention relates to an isoxazoline derivative having an ester portion, which is a prodrug of a caspase inhibitor, and a pharmaceutical composition...
SourceID epo
SourceType Open Access Repository
SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Title PRODRUG OF CASPASE INHIBITOR
URI https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201109&DB=EPODOC&locale=&CC=KR&NR=20200126928A
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMTK1SLJItkzStbSwNNA1SbNM07U0tkzWTbNIBLb2DVPMDZNA-519_cw8Qk28IkwjmBhyYHthwOeEloMPRwTmqGRgfi8Bl9cFiEEsF_DaymL9pEygUL69W4itixq0dwyuzSzVXJxsXQP8Xfyd1Zydbb2D1PyCwHLAstjM0sjCkZmBFdSQBp207xrmBNqXUoBcqbgJMrAFAM3LKxFiYMrOF2bgdIbdvSbMwOELnfIGMqG5r1iEQSYgyN8lKNRdwd9NwdkxOMAx2FXB08_D08kzxD9IlEHZzTXE2UMXaE083Ffx3kHIbjIWY2AB9vdTJRgUUkzMgDWGQaJBiomxSWpqaiKwU2RkkGSYlGqeapZqbizJIIPPJCn80tIMXCAueDudpQwDS0lRaaossF4tSZIDBwcAkZ13Ig
link.rule.ids 230,309,786,891,25594,76904
linkProvider European Patent Office
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1bS8MwFD7MKc43nYqXqQWlb8Xe1jYPRdabrdva0nWyt7J0GYjihqv49z0Nm-5pbyEHTi5w8uVL8p0APKhdi1oloRKxiCzpczKXiEZKaW5NcbevzEyF1nrnYWyEY_1l0p004GOjheF5Qn94ckSMqBLjveLr9fL_EMvjbytXj_QNqxZPQW574podczQjoufYfpp4iSu6rt3PxDjjNlyLDaJavT3YN5EU1pn2_Ven1qUst0ElOIaDFP19VifQeF-0oeVu_l5rw-FwfeWNxXX0rU6hk2aJl42fhSQQ3N4o7Y18IYrDyInyJDuD-8DP3VDCZoq_URX9bLtP2jk0ke-zCxBmuoGIIU_lma7pjLEpkiJVpgplJjOYqV1CZ5enq93mO2iF-XBQDKK4fw1HtYlL60gHmtXXN7tBjK3oLZ-aX0mZeg0
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=PRODRUG+OF+CASPASE+INHIBITOR&rft.inventor=SONG+JEONG+UK&rft.inventor=KIM+JEONG+AE&rft.inventor=BAEK+JAE+UK&rft.inventor=CHOI+SEI+HYUN&rft.inventor=PARK+AH+BYEOL&rft.inventor=PARK+HYUN+SEO&rft.inventor=MOON+HEE+JEONG&rft.inventor=KANG+SO+YEONG&rft.inventor=KIM+SUNG+WON&rft.date=2020-11-09&rft.externalDBID=A&rft.externalDocID=KR20200126928A