CASP2 - RNA DOUBLE-STRANDED RNA COMPOUNDS TO CASP2 AND USES THEREOF

• Main Authors: ERLICH SHAI, OZDEN RABIA, THOMPSON JAMES D
• Format: Patent
• Language: English; Korean
• Published: 11.12.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

본 상세한 설명은 안질환, 장애 또는 손상으로 고통받거나 또는 이들로 발전할 위험이 있는 환자들을 치료하는 방법에 관한 것이고, 그리고 CASP2 발현을 하향-조절하는 이중-가닥 RNA 화합물 또는 그의 약제학적으로 수용가능한 염을 사용하는 치료요법을 포함한다. The present disclosure relates to methods of treating a patient suffering from or at risk of developing an ocular disease, disorder or injury, and includes treatment regimens using a double-stranded RNA compound that down-regulates CASP2 expression, or a pharmaceutically acceptable salt thereof.