4 ANTI-VEGF/DLL4 DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF

다가이고 다중 특이적인 결합 단백질, 상기 결합 단백질의 제조 방법, 및 이상 DLL4 및/또는 VEGF 발현 또는 활성을 특징으로 하는, 암, 종양, 및/또는 다른 혈관신생-의존적 질환의 진단, 모니터링, 억제, 예방 및/또는 치료시의 상기 결합 단백질의 용도가 본원에 개시된다. Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis,...

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Main Authors HAASCH DEANNA L, LAPPE SUSAN E, CHARI RAVI, LI YINGCHUN, AMBROSI DOMINIC J, GU JIJIE, NAUMOVSKI LOUIE, GUPTA SUPRIYA, CAO XIANHUA, HICKSON JONATHAN A, ZAMIRI CAMELLIA
Format Patent
LanguageEnglish
Korean
Published 19.08.2019
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Abstract 다가이고 다중 특이적인 결합 단백질, 상기 결합 단백질의 제조 방법, 및 이상 DLL4 및/또는 VEGF 발현 또는 활성을 특징으로 하는, 암, 종양, 및/또는 다른 혈관신생-의존적 질환의 진단, 모니터링, 억제, 예방 및/또는 치료시의 상기 결합 단백질의 용도가 본원에 개시된다. Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis, monitoring, inhibition, prevention and/or treatment of cancers, tumors, and/or other angiogenesis-dependent diseases diseases characterized by aberrant DLL4 and/or VEGF expression or activity.
AbstractList 다가이고 다중 특이적인 결합 단백질, 상기 결합 단백질의 제조 방법, 및 이상 DLL4 및/또는 VEGF 발현 또는 활성을 특징으로 하는, 암, 종양, 및/또는 다른 혈관신생-의존적 질환의 진단, 모니터링, 억제, 예방 및/또는 치료시의 상기 결합 단백질의 용도가 본원에 개시된다. Disclosed herein are multivalent and multispecific binding proteins, methods of making the binding proteins, and their uses in the diagnosis, monitoring, inhibition, prevention and/or treatment of cancers, tumors, and/or other angiogenesis-dependent diseases diseases characterized by aberrant DLL4 and/or VEGF expression or activity.
Author HICKSON JONATHAN A
GU JIJIE
HAASCH DEANNA L
CHARI RAVI
GUPTA SUPRIYA
CAO XIANHUA
LAPPE SUSAN E
AMBROSI DOMINIC J
ZAMIRI CAMELLIA
NAUMOVSKI LOUIE
LI YINGCHUN
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– fullname: GUPTA SUPRIYA
– fullname: CAO XIANHUA
– fullname: HICKSON JONATHAN A
– fullname: ZAMIRI CAMELLIA
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Snippet 다가이고 다중 특이적인 결합 단백질, 상기 결합 단백질의 제조 방법, 및 이상 DLL4 및/또는 VEGF 발현 또는 활성을 특징으로 하는, 암, 종양, 및/또는 다른 혈관신생-의존적 질환의 진단, 모니터링, 억제, 예방 및/또는 치료시의 상기 결합 단백질의 용도가 본원에 개시된다....
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title 4 ANTI-VEGF/DLL4 DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF
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