VECTORS FOR EXPRESSION OF PROSTATE-ASSOCIATED ANTIGENS

• Main Authors: BINDER JOSEPH JOHN, CHO HELEN KIM
• Format: Patent
• Language: English; Korean
• Published: 02.08.2019
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

본 개시내용은 (a) 2, 3개, 또는 그 초과의 면역원성 PAA 폴리펩티드를 코딩하는 다중-항원 구축물을 포함하는 벡터; (b) 상기 벡터를 포함하는 조성물, (c) 전립선암에 대한 면역 반응을 유도하거나 또는 이를 치료하기 위한 상기 벡터 및 조성물의 사용에 관련된 방법을 제공한다. The present disclosure provides (a) vectors comprising a multi-antigen construct encoding two, three, or more immunogenic PAA polypeptides; (b) compositions comprising the vectors, (c) methods relating to uses of the vectors and compositions for eliciting an immune response or for treating prostate cancers.