12- 12-Diol type polyol derivative compound and preparation method thereof and anti-microbial composition containing it

• Main Author: KIM KYOUNG WOOK
• Format: Patent
• Language: English; Korean
• Published: 26.07.2019
• Subjects: ACYCLIC OR CARBOCYCLIC COMPOUNDS; CHEMISTRY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS

The present invention relates to a polyol derivative compound having a 1,2-diol structure represented by chemical formula 1, a method of preparing the same, and an anti-microbial composition containing the compound as an active ingredient. In the chemical formula: R1 is nitrogen (N) or sulfur (S); and R2 is OH or C2 alkyl. According to the present invention, the polyol derivative compound having a 1,2-diol structure represented by the chemical formula 1 exhibits excellent anti-microbial activities better than 1,2-hexanediol, which is known to have the best anti-microbial activity among polyols, thereby being effectively used as a preservative for a food product, a medicine, a cosmetic, and the like to prevent spoilage caused by microorganisms. 본 발명은 하기 화학식 1로 표시되는 1,2-디올 구조를 갖는 폴리올 유도체 화합물, 그 제조방법, 및 상기 화합물을 유효성분으로 함유하는 항균 조성물에 관한 것이다. [화학식 1]상기 식에서, R1은 나이트로전(N) 또는 설퍼(S) 이고, R2는 OH 또는 C2 알킬이다. 본 발명에 따르면, 상기 화학식 1로 표시되는 1,2-디올 구조를 갖는 폴리올 유도체 화합물은 기존의 폴리올 중에서 가장 좋은 항균력을 나타낸다고 알려진 1,2-헥산디올보다 우수한 항균력을 나타내므로, 식품, 의약품, 화장품 등의 많은 제품들은 미생물에 의한 부패를 막아주는 방부제로서 효과적으로 사용될 수 있다.