키메라 항원 수용체 및 PD-1 억제제의 조합 요법
PD-1 억제제와 조합하여, 항원, 예를 들어 CD19에 특이적인 키메라 항원 수용체(CAR)를 발현하는 세포를 투여하는 것을 포함하는 질환, 예를 들어 암, 예를 들어 항원, 예를 들어 CD19의 발현과 연관된 질환을 치료하기 위한 조성물 및 방법이 제공된다. Provided are compositions and methods for treating diseases, e.g., cancers, e.g., diseases associated with expression of an antigen, e.g., CD 19, compris...
Saved in:
Main Authors | , , , , , , , , , , , , , |
---|---|
Format | Patent |
Language | Korean |
Published |
02.04.2019
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | PD-1 억제제와 조합하여, 항원, 예를 들어 CD19에 특이적인 키메라 항원 수용체(CAR)를 발현하는 세포를 투여하는 것을 포함하는 질환, 예를 들어 암, 예를 들어 항원, 예를 들어 CD19의 발현과 연관된 질환을 치료하기 위한 조성물 및 방법이 제공된다.
Provided are compositions and methods for treating diseases, e.g., cancers, e.g., diseases associated with expression of an antigen, e.g., CD 19, comprising administering a cell that expresses a chimeric antigen receptor (CAR) specific to the antigen, e.g., CD19, in combination with a PD-1 inhibitor. |
---|---|
AbstractList | PD-1 억제제와 조합하여, 항원, 예를 들어 CD19에 특이적인 키메라 항원 수용체(CAR)를 발현하는 세포를 투여하는 것을 포함하는 질환, 예를 들어 암, 예를 들어 항원, 예를 들어 CD19의 발현과 연관된 질환을 치료하기 위한 조성물 및 방법이 제공된다.
Provided are compositions and methods for treating diseases, e.g., cancers, e.g., diseases associated with expression of an antigen, e.g., CD 19, comprising administering a cell that expresses a chimeric antigen receptor (CAR) specific to the antigen, e.g., CD19, in combination with a PD-1 inhibitor. |
Author | SHUSTER STEPHEN JUNE CARL H BROGDON JENNIFER GRUPP STEPHAN LACEY SIMON QUINTAS CARDAMA ALFONSO MAUDE SHANNON HOWARD DANNY ROLAND JR CAMERON JOHN SCOTT ANAK OEZLEM CHOU WILLIAM ISAACS RANDI MELENHORST JAN J BILIC SANELA |
Author_xml | – fullname: BROGDON JENNIFER – fullname: CAMERON JOHN SCOTT – fullname: CHOU WILLIAM – fullname: BILIC SANELA – fullname: ANAK OEZLEM – fullname: SHUSTER STEPHEN – fullname: HOWARD DANNY ROLAND JR – fullname: ISAACS RANDI – fullname: JUNE CARL H – fullname: QUINTAS CARDAMA ALFONSO – fullname: GRUPP STEPHAN – fullname: LACEY SIMON – fullname: MELENHORST JAN J – fullname: MAUDE SHANNON |
BookMark | eNrjYmDJy89L5WSwe9u05PXKKa_n7lF4O3Xtm9kTFN50zHgza-WbTVsUXm_oVwhw0TVUeDNt65sFc0Bo7gyFNws3vJ26UuHNrCmvN03lYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx3kFGBoaWBgbGJqYWFo7GxKkCAJpcQnk |
ContentType | Patent |
DBID | EVB |
DatabaseName | esp@cenet |
DatabaseTitleList | |
Database_xml | – sequence: 1 dbid: EVB name: esp@cenet url: http://worldwide.espacenet.com/singleLineSearch?locale=en_EP sourceTypes: Open Access Repository |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Chemistry Sciences |
ExternalDocumentID | KR20190034588A |
GroupedDBID | EVB |
ID | FETCH-epo_espacenet_KR20190034588A3 |
IEDL.DBID | EVB |
IngestDate | Fri Aug 30 05:40:42 EDT 2024 |
IsOpenAccess | true |
IsPeerReviewed | false |
IsScholarly | false |
Language | Korean |
LinkModel | DirectLink |
MergedId | FETCHMERGED-epo_espacenet_KR20190034588A3 |
Notes | Application Number: KR20197005490 |
OpenAccessLink | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190402&DB=EPODOC&CC=KR&NR=20190034588A |
ParticipantIDs | epo_espacenet_KR20190034588A |
PublicationCentury | 2000 |
PublicationDate | 20190402 |
PublicationDateYYYYMMDD | 2019-04-02 |
PublicationDate_xml | – month: 04 year: 2019 text: 20190402 day: 02 |
PublicationDecade | 2010 |
PublicationYear | 2019 |
RelatedCompanies | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA NOVARTIS AG |
RelatedCompanies_xml | – name: NOVARTIS AG – name: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
Score | 3.1552546 |
Snippet | PD-1 억제제와 조합하여, 항원, 예를 들어 CD19에 특이적인 키메라 항원 수용체(CAR)를 발현하는 세포를 투여하는 것을 포함하는 질환, 예를 들어 암, 예를 들어 항원, 예를 들어 CD19의 발현과 연관된 질환을 치료하기 위한 조성물 및 방법이 제공된다.
Provided are... |
SourceID | epo |
SourceType | Open Access Repository |
SubjectTerms | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
Title | 키메라 항원 수용체 및 PD-1 억제제의 조합 요법 |
URI | https://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20190402&DB=EPODOC&locale=&CC=KR&NR=20190034588A |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMTE1Bo0EWuimAVsLuibAFi4wS6VZ6JomGluaJKYYm1mAL5vw9TPzCDXxijCNYGLIge2FAZ8TWg4-HBGYo5KB-b0EXF4XIAaxXMBrK4v1kzKBQvn2biG2LmrQ3jGwdgP2h9RcnGxdA_xd_J3VnJ1tvYPU_IIgcgbGoH2ZjswMrMCGtDkoP7iGOYH2pRQgVypuggxsAUDz8kqEGJiy84UZOJ1hd68JM3D4Qqe8gUxo7isWYbB727Tk9copr-fuUXg7de2b2RMU3nTMeDNr5ZtNWxReb-hXCHDRNVR4M23rmwVzQGjuDIU3Cze8nbpS4c2sKa83TRVlUHZzDXH20AU6JB7u73jvIGRXG4sxsOTl56VKMCiYJ1uappqlJgPLBmOTNDPLJHNQrWwAOnjF2CIxOVmSQQafSVL4paUZuEBc8PIUIxkGlpKi0lRZYM1bkiQHDjAATUmVFg |
link.rule.ids | 230,309,783,888,25576,76876 |
linkProvider | European Patent Office |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwY2BQMTE1Bo0EWuimAVsLuibAFi4wS6VZ6JomGluaJKYYm1mAL5vw9TPzCDXxijCNYGLIge2FAZ8TWg4-HBGYo5KB-b0EXF4XIAaxXMBrK4v1kzKBQvn2biG2LmrQ3jGwdgP2h9RcnGxdA_xd_J3VnJ1tvYPU_IIgcgbGoH2ZjswMrMBGtjkoP7iGOYH2pRQgVypuggxsAUDz8kqEGJiy84UZOJ1hd68JM3D4Qqe8gUxo7isWYbB727Tk9copr-fuUXg7de2b2RMU3nTMeDNr5ZtNWxReb-hXCHDRNVR4M23rmwVzQGjuDIU3Cze8nbpS4c2sKa83TRVlUHZzDXH20AU6JB7u73jvIGRXG4sxsOTl56VKMCiYJ1uappqlJgPLBmOTNDPLJHNQrWwAOnjF2CIxOVmSQQafSVL4peUZOD1CfH3ifTz9vKUZuEBS4KUqRjIMLCVFpamywFq4JEkOHHgAdumYCQ |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Apatent&rft.title=%ED%82%A4%EB%A9%94%EB%9D%BC+%ED%95%AD%EC%9B%90+%EC%88%98%EC%9A%A9%EC%B2%B4+%EB%B0%8F+PD-1+%EC%96%B5%EC%A0%9C%EC%A0%9C%EC%9D%98+%EC%A1%B0%ED%95%A9+%EC%9A%94%EB%B2%95&rft.inventor=BROGDON+JENNIFER&rft.inventor=CAMERON+JOHN+SCOTT&rft.inventor=CHOU+WILLIAM&rft.inventor=BILIC+SANELA&rft.inventor=ANAK+OEZLEM&rft.inventor=SHUSTER+STEPHEN&rft.inventor=HOWARD+DANNY+ROLAND+JR&rft.inventor=ISAACS+RANDI&rft.inventor=JUNE+CARL+H&rft.inventor=QUINTAS+CARDAMA+ALFONSO&rft.inventor=GRUPP+STEPHAN&rft.inventor=LACEY+SIMON&rft.inventor=MELENHORST+JAN+J&rft.inventor=MAUDE+SHANNON&rft.date=2019-04-02&rft.externalDBID=A&rft.externalDocID=KR20190034588A |